CRCGN010_HEPG2_24H:D23 Gene Set
Genes
49 genes differentially expressed following the CRCGN010_HEPG2_24H:D23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHMP6
|
charged multivesicular body protein 6
|
9.09829
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
8.41403
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
6.54141
|
|
UBQLN2
|
ubiquilin 2
|
5.81602
|
|
PRR15L
|
proline rich 15-like
|
5.45389
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
4.66166
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.6374
|
|
LCN2
|
lipocalin 2
|
4.41077
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.90674
|
|
PLS1
|
plastin 1
|
3.6985
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.66739
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.61367
|
|
KIF5C
|
kinesin family member 5C
|
3.44734
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.34588
|
|
CBR3
|
carbonyl reductase 3
|
3.34229
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.21927
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.12522
|
|
CHAC1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
3.03586
|
|
VGLL4
|
vestigial-like family member 4
|
2.73804
|
|
JADE2
|
jade family PHD finger 2
|
2.70189
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.48455
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.30148
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.26808
|
|
CHN1
|
chimerin 1
|
2.17364
|
|
RAB31
|
RAB31, member RAS oncogene family
|
2.06229
|
|
CYREN
|
cell cycle regulator of NHEJ
|
2.05921
|
|
MEST
|
mesoderm specific transcript
|
2.03497
|
|
MMP2
|
matrix metallopeptidase 2
|
2.00281
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
TLR4
|
toll-like receptor 4
|
-7.33823
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.01928
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.30796
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.30117
|
|
HMG20B
|
high mobility group 20B
|
-4.05301
|
|
TUBB6
|
tubulin, beta 6 class V
|
-4.03329
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.00747
|
|
RAI14
|
retinoic acid induced 14
|
-2.80873
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.79631
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.72396
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.67888
|
|
CAB39
|
calcium binding protein 39
|
-2.46693
|
|
EBNA1BP2
|
EBNA1 binding protein 2
|
-2.44951
|
|
RNF167
|
ring finger protein 167
|
-2.2719
|
|
WASHC4
|
WASH complex subunit 4
|
-2.24671
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.18385
|
|
BNIP2
|
BCL2/adenovirus E1B 19kDa interacting protein 2
|
-2.18003
|
|
UBE2W
|
ubiquitin-conjugating enzyme E2W (putative)
|
-2.02987
|
|
MOCS2
|
molybdenum cofactor synthesis 2
|
-2.02053
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.00205
|
