CRCGN010_HEPG2_24H:D24 Gene Set
Genes
46 genes differentially expressed following the CRCGN010_HEPG2_24H:D24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
5.94831
|
|
MAP7
|
microtubule-associated protein 7
|
5.59111
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.05651
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.26429
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.98049
|
|
CHN1
|
chimerin 1
|
3.75538
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
3.68297
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
3.44757
|
|
MYLK
|
myosin light chain kinase
|
3.29867
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
3.0287
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.89793
|
|
GADD45A
|
growth arrest and DNA-damage-inducible, alpha
|
2.67611
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.63785
|
|
CBR3
|
carbonyl reductase 3
|
2.61781
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.58433
|
|
CREG1
|
cellular repressor of E1A-stimulated genes 1
|
2.31041
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.21558
|
|
CYCS
|
cytochrome c, somatic
|
2.21031
|
|
STXBP2
|
syntaxin binding protein 2
|
2.20745
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.16128
|
|
SFTPB
|
surfactant protein B
|
2.12906
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.04852
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-5.71498
|
|
CDC20
|
cell division cycle 20
|
-4.49975
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-4.21073
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.13823
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-4.12302
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
-3.97371
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.96217
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.79114
|
|
CCNB2
|
cyclin B2
|
-3.72754
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.57162
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.39796
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.26244
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.01242
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.45068
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.36001
|
|
LDHD
|
lactate dehydrogenase D
|
-2.33895
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-2.21369
|
|
RNF167
|
ring finger protein 167
|
-2.20414
|
|
STX4
|
syntaxin 4
|
-2.12598
|
|
STMN1
|
stathmin 1
|
-2.11652
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
-2.10529
|
|
BCL9
|
B-cell CLL/lymphoma 9
|
-2.03695
|
|
FRG1
|
FSHD region gene 1
|
-2.03257
|
|
MRFAP1L1
|
Morf4 family associated protein 1-like 1
|
-2.01614
|
