| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | o,o-dimethyl s-[(4-oxo-1,2,3-benzotriazin-3(4h)-yl)methyl] dithiophosphate 1.32 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN010_HEPG2_24H:E05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 6.58809 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.43294 |
| STIMATE | STIM activating enhancer | 5.04749 |
| LPAR2 | lysophosphatidic acid receptor 2 | 4.57567 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.42965 |
| CCNF | cyclin F | 3.91054 |
| CHMP6 | charged multivesicular body protein 6 | 3.8679 |
| NOTCH1 | notch 1 | 3.83866 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.57288 |
| ZNF589 | zinc finger protein 589 | 3.3921 |
| E2F2 | E2F transcription factor 2 | 3.30755 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 3.11118 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 3.0885 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.95443 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.82217 |
| NPY | neuropeptide Y | 2.79034 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.72444 |
| MSRA | methionine sulfoxide reductase A | 2.72194 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 2.61526 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.56528 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.55636 |
| RPA3 | replication protein A3, 14kDa | 2.4647 |
| SIRT3 | sirtuin 3 | 2.45447 |
| CYCS | cytochrome c, somatic | 2.43193 |
| MAP7 | microtubule-associated protein 7 | 2.42779 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.33223 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.2375 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.17751 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.15104 |
| NOSIP | nitric oxide synthase interacting protein | 2.1298 |
| EVL | Enah/Vasp-like | 2.10699 |
| GPATCH8 | G patch domain containing 8 | 2.07064 |
| PLSCR3 | phospholipid scramblase 3 | 2.06773 |
| CTSL | cathepsin L | 2.01304 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -7.62956 |
| ZNF586 | zinc finger protein 586 | -6.54543 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.81604 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -4.34015 |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | -4.24724 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -4.23312 |
| DSG2 | desmoglein 2 | -4.19999 |
| TLR4 | toll-like receptor 4 | -3.91131 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.86728 |
| PCNA | proliferating cell nuclear antigen | -3.68271 |
| RNF167 | ring finger protein 167 | -3.5183 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.51418 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.41645 |
| TRIB3 | tribbles pseudokinase 3 | -3.30602 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.27432 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -2.75388 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.74031 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -2.71959 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.51143 |
| PLA2G15 | phospholipase A2, group XV | -2.46834 |
| GOLT1B | golgi transport 1B | -2.4404 |
| ATAD2B | ATPase family, AAA domain containing 2B | -2.37721 |
| FAT1 | FAT atypical cadherin 1 | -2.37228 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.32326 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.3201 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -2.15522 |
| LDHD | lactate dehydrogenase D | -2.13771 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.1276 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -2.09076 |
| CHMP4B | charged multivesicular body protein 4B | -2.09055 |
| VAT1 | vesicle amine transport 1 | -2.08485 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.07418 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -2.07387 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.06711 |
| RNFT1-DT | RNFT1 divergent transcript | -2.06595 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.03621 |
