CRCGN010_HEPG2_24H:E06 Gene Set
Genes
39 genes differentially expressed following the CRCGN010_HEPG2_24H:E06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
7.59465
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.32985
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.75825
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
4.36834
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
4.33033
|
|
CSK
|
c-src tyrosine kinase
|
4.23633
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.97683
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.95152
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
3.70934
|
|
MAP7
|
microtubule-associated protein 7
|
3.51896
|
|
STIMATE
|
STIM activating enhancer
|
3.45206
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
3.4003
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.11728
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.8721
|
|
JADE2
|
jade family PHD finger 2
|
2.8349
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.73803
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.64918
|
|
MARF1
|
meiosis regulator and mRNA stability factor 1
|
2.57786
|
|
IDE
|
insulin-degrading enzyme
|
2.50164
|
|
CHN1
|
chimerin 1
|
2.42045
|
|
RRAGA
|
Ras-related GTP binding A
|
2.25577
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.1585
|
|
PIK3CA
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
|
2.10978
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-7.79945
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.59419
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.58349
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.46288
|
|
DNM1L
|
dynamin 1-like
|
-4.44162
|
|
TP53BP2
|
tumor protein p53 binding protein 2
|
-4.28507
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.04805
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.91219
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.80417
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-3.34252
|
|
CD320
|
CD320 molecule
|
-2.71961
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.48177
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.37757
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.33383
|
|
TRIB1
|
tribbles pseudokinase 1
|
-2.26328
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.22127
|
