CRCGN010_HEPG2_24H:E08 Gene Set
Genes
40 genes differentially expressed following the CRCGN010_HEPG2_24H:E08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CSK
|
c-src tyrosine kinase
|
3.55627
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.3635
|
|
SATB1
|
SATB homeobox 1
|
3.23113
|
|
STK10
|
serine/threonine kinase 10
|
3.01988
|
|
CDC45
|
cell division cycle 45
|
2.97467
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.9598
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.71312
|
|
INTS3
|
integrator complex subunit 3
|
2.62067
|
|
NMU
|
neuromedin U
|
2.60317
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.44831
|
|
FZD7
|
frizzled class receptor 7
|
2.38675
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.26942
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.26577
|
|
ZNF589
|
zinc finger protein 589
|
2.25474
|
|
MMD
|
monocyte to macrophage differentiation-associated
|
2.21777
|
|
MAP7
|
microtubule-associated protein 7
|
2.09346
|
|
SCRN1
|
secernin 1
|
2.03143
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.01822
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-6.61133
|
|
CCNB2
|
cyclin B2
|
-6.2323
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.98208
|
|
SCAND1
|
SCAN domain containing 1
|
-4.44047
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.9399
|
|
VAT1
|
vesicle amine transport 1
|
-3.53053
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.48593
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.44237
|
|
CD320
|
CD320 molecule
|
-3.1808
|
|
LDHD
|
lactate dehydrogenase D
|
-3.12557
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.021
|
|
NISCH
|
nischarin
|
-2.9256
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.47273
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.44117
|
|
TBCB
|
tubulin folding cofactor B
|
-2.43613
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.40013
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.26096
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.2235
|
|
SESN1
|
sestrin 1
|
-2.20227
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
-2.18263
|
|
TMEM147
|
transmembrane protein 147
|
-2.0892
|
|
S100A6
|
S100 calcium binding protein A6
|
-2.0889
|
