| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | o,o-dimethyl s-[2-(methylamino)-2-oxoethyl] dithiophosphate 5.15 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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62 genes differentially expressed following the CRCGN010_HEPG2_24H:E09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NMU | neuromedin U | 7.13559 |
| MEST | mesoderm specific transcript | 5.59353 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.56179 |
| LCN2 | lipocalin 2 | 5.17203 |
| EPHB2 | EPH receptor B2 | 5.06535 |
| PIH1D1 | PIH1 domain containing 1 | 4.53227 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 3.85863 |
| MAP7 | microtubule-associated protein 7 | 3.72354 |
| AXIN1 | axin 1 | 3.57232 |
| MOK | MOK protein kinase | 3.20507 |
| HSPA8 | heat shock 70kDa protein 8 | 3.12497 |
| PRR15L | proline rich 15-like | 3.08328 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.8388 |
| CCNH | cyclin H | 2.76039 |
| KIFBP | kinesin family binding protein | 2.73931 |
| LSR | lipolysis stimulated lipoprotein receptor | 2.7371 |
| TESK1 | testis-specific kinase 1 | 2.68809 |
| RPL39L | ribosomal protein L39-like | 2.66414 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.65067 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.64795 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 2.57803 |
| SHB | Src homology 2 domain containing adaptor protein B | 2.5592 |
| TSPAN6 | tetraspanin 6 | 2.52353 |
| TEX10 | testis expressed 10 | 2.50657 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.27337 |
| NOSIP | nitric oxide synthase interacting protein | 2.24434 |
| EPHA3 | EPH receptor A3 | 2.19538 |
| EHF | ets homologous factor | 2.18633 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.15409 |
| TAC4 | tachykinin 4 (hemokinin) | 2.10487 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 2.08818 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -5.26885 |
| CCDC86 | coiled-coil domain containing 86 | -4.94314 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.73619 |
| ZNF586 | zinc finger protein 586 | -4.52257 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.45437 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -4.07178 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -3.84002 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.81404 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -3.46204 |
| NGRN | neugrin, neurite outgrowth associated | -3.42221 |
| PGM1 | phosphoglucomutase 1 | -3.34805 |
| HEATR1 | HEAT repeat containing 1 | -3.23587 |
| SNX11 | sorting nexin 11 | -3.11068 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -3.03224 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -3.00385 |
| MVP | major vault protein | -2.69618 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.5628 |
| DPH2 | DPH2 homolog (S. cerevisiae) | -2.53042 |
| CAB39 | calcium binding protein 39 | -2.43205 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -2.40527 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.39277 |
| SPAG7 | sperm associated antigen 7 | -2.38344 |
| SPAG4 | sperm associated antigen 4 | -2.37847 |
| PRKCD | protein kinase C, delta | -2.37121 |
| TLR4 | toll-like receptor 4 | -2.28377 |
| FHL2 | four and a half LIM domains 2 | -2.19607 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 | -2.15886 |
| CD151 | CD151 molecule (Raph blood group) | -2.13097 |
| RASA4B | RAS p21 protein activator 4B | -2.10272 |
| REV1 | REV1, polymerase (DNA directed) | -2.07638 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z | -2.0646 |
