CRCGN010_HEPG2_24H:E12 Gene Set
Genes
47 genes differentially expressed following the CRCGN010_HEPG2_24H:E12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
7.01367
|
|
MAP7
|
microtubule-associated protein 7
|
6.22242
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
4.66427
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
4.46097
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.34204
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.09713
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.01252
|
|
EVL
|
Enah/Vasp-like
|
2.88595
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.7815
|
|
MYLK
|
myosin light chain kinase
|
2.76449
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.51069
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.3591
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.23851
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.21354
|
|
STAG3
|
stromal antigen 3
|
2.19926
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.14704
|
|
RCC1
|
regulator of chromosome condensation 1
|
2.08562
|
|
ENTPD2
|
ectonucleoside triphosphate diphosphohydrolase 2
|
2.08468
|
|
SQOR
|
sulfide quinone oxidoreductase
|
2.05394
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.04637
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-6.75327
|
|
ZNF586
|
zinc finger protein 586
|
-6.52188
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.70564
|
|
GNAS
|
GNAS complex locus
|
-4.56133
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.40328
|
|
CD320
|
CD320 molecule
|
-4.20545
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.11578
|
|
GOLT1B
|
golgi transport 1B
|
-4.07899
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.08452
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-2.98075
|
|
TES
|
testin LIM domain protein
|
-2.84124
|
|
PSME1
|
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
|
-2.81167
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.73839
|
|
CCNB2
|
cyclin B2
|
-2.67742
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.61114
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.60392
|
|
TLR4
|
toll-like receptor 4
|
-2.58459
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.57463
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.53681
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.44197
|
|
SNX11
|
sorting nexin 11
|
-2.3789
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.30071
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.07694
|
|
ZNF134
|
zinc finger protein 134
|
-2.06572
|
|
RPS5
|
ribosomal protein S5
|
-2.04544
|
|
ZNF180
|
zinc finger protein 180
|
-2.03373
|
|
LY86
|
lymphocyte antigen 86
|
-2.01547
|
