CRCGN010_HEPG2_24H:E16 Gene Set
Genes
54 genes differentially expressed following the CRCGN010_HEPG2_24H:E16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
6.5164
|
|
LOC122526780
|
uncharacterized LOC122526780
|
4.96303
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
4.47008
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.42851
|
|
CHN1
|
chimerin 1
|
3.90356
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.78017
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.10018
|
|
MEST
|
mesoderm specific transcript
|
3.0987
|
|
TBXA2R
|
thromboxane A2 receptor
|
3.09139
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.96112
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.85887
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
2.81692
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
2.80086
|
|
ICAM1
|
intercellular adhesion molecule 1
|
2.76991
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.75291
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.6843
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.68166
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
2.67944
|
|
GPATCH8
|
G patch domain containing 8
|
2.47237
|
|
KIF5C
|
kinesin family member 5C
|
2.45524
|
|
SATB1
|
SATB homeobox 1
|
2.43602
|
|
CCNA1
|
cyclin A1
|
2.37369
|
|
E2F2
|
E2F transcription factor 2
|
2.37311
|
|
NOTCH1
|
notch 1
|
2.34525
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.1719
|
|
CEP57
|
centrosomal protein 57kDa
|
2.13318
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.10893
|
|
GATA2
|
GATA binding protein 2
|
2.0662
|
|
MSRA
|
methionine sulfoxide reductase A
|
2.01409
|
|
CXCL8
|
chemokine (C-X-C motif) ligand 8
|
2.01365
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-5.7349
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.38972
|
|
RNF167
|
ring finger protein 167
|
-4.41018
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-4.33566
|
|
LDHD
|
lactate dehydrogenase D
|
-4.16306
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-4.09178
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-4.04871
|
|
CDC25B
|
cell division cycle 25B
|
-3.77064
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.75986
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.40041
|
|
GNAS
|
GNAS complex locus
|
-3.30788
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.1416
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
-3.05987
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.00816
|
|
USP6NL
|
USP6 N-terminal like
|
-2.44461
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.43654
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.38628
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.2892
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.22816
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.20139
|
|
MPV17L-BMERB1
|
MPV17L-BMERB1 readthrough
|
-2.1912
|
|
NVL
|
nuclear VCP-like
|
-2.13891
|
|
DSG2
|
desmoglein 2
|
-2.11181
|
|
SPAG4
|
sperm associated antigen 4
|
-2.04572
|
