CRCGN010_HEPG2_24H:E17 Gene Set
Genes
56 genes differentially expressed following the CRCGN010_HEPG2_24H:E17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
6.0403
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.6404
|
|
MYLK
|
myosin light chain kinase
|
5.56831
|
|
LCN2
|
lipocalin 2
|
5.49767
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.55385
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
4.18722
|
|
JADE2
|
jade family PHD finger 2
|
4.16051
|
|
E2F2
|
E2F transcription factor 2
|
4.03498
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
4.02064
|
|
NOTCH1
|
notch 1
|
3.87892
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
3.76039
|
|
EVL
|
Enah/Vasp-like
|
3.45321
|
|
MOK
|
MOK protein kinase
|
3.17261
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
3.16128
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.12792
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
3.07641
|
|
PMM2
|
phosphomannomutase 2
|
3.02951
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.92363
|
|
SPDEF
|
SAM pointed domain containing ETS transcription factor
|
2.82143
|
|
MAP7
|
microtubule-associated protein 7
|
2.82028
|
|
BAX
|
BCL2-associated X protein
|
2.66562
|
|
SIRT3
|
sirtuin 3
|
2.58399
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.42866
|
|
DIXDC1
|
DIX domain containing 1
|
2.35835
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.35791
|
|
NXPH3
|
neurexophilin 3
|
2.26938
|
|
PTK2
|
protein tyrosine kinase 2
|
2.23502
|
|
TSNAXIP1
|
translin-associated factor X interacting protein 1
|
2.23397
|
|
CD33
|
CD33 molecule
|
2.06718
|
|
TNFSF12-TNFSF13
|
TNFSF12-TNFSF13 readthrough
|
2.05141
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.05129
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.00269
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-9.45755
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-7.60302
|
|
TUBB6
|
tubulin, beta 6 class V
|
-4.65534
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-4.47721
|
|
GNAS
|
GNAS complex locus
|
-3.76534
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.65597
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.62335
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-3.3939
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.01832
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.73001
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.66076
|
|
C5
|
complement component 5
|
-2.58839
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.42121
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.39634
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.3907
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.37681
|
|
CHMP2A
|
charged multivesicular body protein 2A
|
-2.34203
|
|
USP6NL
|
USP6 N-terminal like
|
-2.32398
|
|
SCCPDH
|
saccharopine dehydrogenase (putative)
|
-2.3021
|
|
ZNF134
|
zinc finger protein 134
|
-2.26613
|
|
CCNL2
|
cyclin L2
|
-2.15449
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.13836
|
|
TIMM10
|
translocase of inner mitochondrial membrane 10 homolog (yeast)
|
-2.12184
|
|
SCAND1
|
SCAN domain containing 1
|
-2.04992
|
