| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-nitrosopiperidine 39.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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51 genes differentially expressed following the CRCGN010_HEPG2_24H:E19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DYNLT3 | dynein, light chain, Tctex-type 3 | 8.47778 |
| UBQLN2 | ubiquilin 2 | 8.40316 |
| LCN2 | lipocalin 2 | 5.89537 |
| CBR3 | carbonyl reductase 3 | 4.81694 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.57576 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.57255 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.42448 |
| CHMP6 | charged multivesicular body protein 6 | 4.24653 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 3.99483 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 3.88242 |
| ALDOC | aldolase C, fructose-bisphosphate | 3.67671 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.60951 |
| ZFP36 | ZFP36 ring finger protein | 3.58902 |
| ZNF589 | zinc finger protein 589 | 3.49898 |
| NOSIP | nitric oxide synthase interacting protein | 3.10697 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.93611 |
| GPATCH8 | G patch domain containing 8 | 2.7285 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.61449 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 2.53744 |
| LOC122526780 | uncharacterized LOC122526780 | 2.45281 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.40599 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.35538 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.31909 |
| MYLK | myosin light chain kinase | 2.25677 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 2.20147 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.17927 |
| CHN1 | chimerin 1 | 2.03676 |
| IFI44 | interferon-induced protein 44 | 2.00684 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.97502 |
| GTPBP8 | GTP-binding protein 8 (putative) | -4.82242 |
| ADI1 | acireductone dioxygenase 1 | -4.51628 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.39539 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.39345 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.93964 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.75982 |
| DNM1L | dynamin 1-like | -3.67435 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.65637 |
| DERA | deoxyribose-phosphate aldolase (putative) | -3.42376 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.38819 |
| RAI14 | retinoic acid induced 14 | -3.33695 |
| TOR1A | torsin family 1, member A (torsin A) | -2.9619 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.85077 |
| MTFR1 | mitochondrial fission regulator 1 | -2.79742 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.53666 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.34083 |
| GDF15 | growth differentiation factor 15 | -2.33738 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.33333 |
| NGRN | neugrin, neurite outgrowth associated | -2.23943 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.17989 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial | -2.09237 |
| PDZD2 | PDZ domain containing 2 | -2.03983 |