| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-nitrosopiperidine 19.9 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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56 genes differentially expressed following the CRCGN010_HEPG2_24H:E20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 7.20016 |
| MAP7 | microtubule-associated protein 7 | 4.74593 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 3.94905 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 3.76819 |
| ATP11B | ATPase, class VI, type 11B | 3.69453 |
| CSK | c-src tyrosine kinase | 3.60654 |
| SQOR | sulfide quinone oxidoreductase | 3.57215 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.55214 |
| CYCS | cytochrome c, somatic | 3.43717 |
| SATB1 | SATB homeobox 1 | 3.26487 |
| DENND2D | DENN/MADD domain containing 2D | 3.24473 |
| NOTCH1 | notch 1 | 3.212 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.00513 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.84844 |
| UBQLN2 | ubiquilin 2 | 2.68462 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.3704 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.2793 |
| PRR15L | proline rich 15-like | 2.21998 |
| ADAM10 | ADAM metallopeptidase domain 10 | 2.20821 |
| COPS7A | COP9 signalosome subunit 7A | 2.18887 |
| MEST | mesoderm specific transcript | 2.16863 |
| LIN37 | lin-37 DREAM MuvB core complex component | 2.15245 |
| VGLL4 | vestigial-like family member 4 | 2.04993 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.04602 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.02714 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -6.78946 |
| LDHD | lactate dehydrogenase D | -6.42589 |
| CHMP4B | charged multivesicular body protein 4B | -6.31648 |
| ZNF586 | zinc finger protein 586 | -6.02408 |
| CCNB2 | cyclin B2 | -5.93447 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.88657 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -3.9925 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.9649 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -3.74792 |
| CDC20 | cell division cycle 20 | -3.6838 |
| ZW10 | zw10 kinetochore protein | -3.30333 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -3.08189 |
| ADI1 | acireductone dioxygenase 1 | -3.03139 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.99617 |
| CCDC86 | coiled-coil domain containing 86 | -2.86446 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.83596 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -2.74078 |
| GOLT1B | golgi transport 1B | -2.63369 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.48907 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.45796 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | -2.32614 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -2.32164 |
| TECR | trans-2,3-enoyl-CoA reductase | -2.29299 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -2.2425 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.15306 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.09744 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -2.02322 |
| TLR4 | toll-like receptor 4 | -2.02056 |
| FOXF1 | forkhead box F1 | -2.01863 |
| CCDC68 | coiled-coil domain containing 68 | -2.01626 |
| CCNH | cyclin H | -2.01397 |
