| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-nitrosopiperidine 9.95 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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60 genes differentially expressed following the CRCGN010_HEPG2_24H:E21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 5.30309 |
| NOTCH1 | notch 1 | 5.15863 |
| LCN2 | lipocalin 2 | 4.96598 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.28565 |
| MAP7 | microtubule-associated protein 7 | 4.2691 |
| PLSCR1 | phospholipid scramblase 1 | 4.01968 |
| CHN1 | chimerin 1 | 3.85572 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.26208 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.1385 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.10288 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 3.02522 |
| PTK2 | protein tyrosine kinase 2 | 2.93752 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.84924 |
| COPS7A | COP9 signalosome subunit 7A | 2.70696 |
| UBQLN2 | ubiquilin 2 | 2.68801 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.67902 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 2.54098 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.53553 |
| NOSIP | nitric oxide synthase interacting protein | 2.53339 |
| TEX10 | testis expressed 10 | 2.52115 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.50492 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 2.43578 |
| PIH1D1 | PIH1 domain containing 1 | 2.41768 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 2.41285 |
| NMRK1 | nicotinamide riboside kinase 1 | 2.40939 |
| STK10 | serine/threonine kinase 10 | 2.36279 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.31728 |
| RAB21 | RAB21, member RAS oncogene family | 2.30208 |
| DIPK1A | divergent protein kinase domain 1A | 2.27898 |
| EDN1 | endothelin 1 | 2.25805 |
| TRIM13 | tripartite motif containing 13 | 2.16421 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 2.09935 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.09307 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -8.16807 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -5.20446 |
| DNM1L | dynamin 1-like | -5.03079 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.85027 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.81431 |
| TLCD3A | TLC domain containing 3A | -3.69366 |
| CAB39 | calcium binding protein 39 | -3.68627 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.5143 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.45301 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.20934 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -3.11857 |
| CDC20 | cell division cycle 20 | -3.11644 |
| LDHD | lactate dehydrogenase D | -2.98965 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.90942 |
| VDAC1 | voltage-dependent anion channel 1 | -2.87087 |
| CCNB2 | cyclin B2 | -2.82859 |
| TXNRD1 | thioredoxin reductase 1 | -2.7557 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.58548 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.46991 |
| HYOU1 | hypoxia up-regulated 1 | -2.43912 |
| PRPF4 | pre-mRNA processing factor 4 | -2.25854 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.12558 |
| TMEM33 | transmembrane protein 33 | -2.11795 |
| BCAS3 | breast carcinoma amplified sequence 3 | -2.09877 |
| SPAG4 | sperm associated antigen 4 | -2.06707 |
| WDR7 | WD repeat domain 7 | -2.01413 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial | -2.01096 |
