CRCGN010_HEPG2_24H:E22 Gene Set
Genes
52 genes differentially expressed following the CRCGN010_HEPG2_24H:E22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.97553
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.82719
|
|
UBQLN2
|
ubiquilin 2
|
4.82358
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.5728
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.49107
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.16375
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.94821
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.76143
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.6072
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.50399
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.49342
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.44514
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
3.06017
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.78538
|
|
SIRT3
|
sirtuin 3
|
2.77444
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.75982
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.54591
|
|
MEST
|
mesoderm specific transcript
|
2.52602
|
|
SNX7
|
sorting nexin 7
|
2.43963
|
|
EVL
|
Enah/Vasp-like
|
2.19179
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.15768
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.08398
|
|
WASF3
|
WAS protein family, member 3
|
2.07533
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.06294
|
|
CDC42BPB
|
CDC42 binding protein kinase beta (DMPK-like)
|
2.02146
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLCD3A
|
TLC domain containing 3A
|
-6.5954
|
|
GNAS
|
GNAS complex locus
|
-5.71051
|
|
LDHD
|
lactate dehydrogenase D
|
-4.65285
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-4.06094
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.67919
|
|
STX4
|
syntaxin 4
|
-3.65617
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.61169
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.58411
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.56238
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.32445
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.12964
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.12084
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-3.07952
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.96822
|
|
ZNF586
|
zinc finger protein 586
|
-2.93467
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.69995
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.68682
|
|
DSG2
|
desmoglein 2
|
-2.58237
|
|
DNM1L
|
dynamin 1-like
|
-2.35327
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.33028
|
|
CDC20
|
cell division cycle 20
|
-2.23663
|
|
WASHC4
|
WASH complex subunit 4
|
-2.21794
|
|
CHGB
|
chromogranin B
|
-2.19957
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.0934
|
|
CLCA4
|
chloride channel accessory 4
|
-2.07903
|
|
SESN1
|
sestrin 1
|
-2.05001
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.00601
|
