CRCGN010_HEPG2_24H:E24 Gene Set
Genes
49 genes differentially expressed following the CRCGN010_HEPG2_24H:E24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PRR15L
|
proline rich 15-like
|
4.65256
|
|
UBQLN2
|
ubiquilin 2
|
4.46602
|
|
CYCS
|
cytochrome c, somatic
|
4.3441
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.59098
|
|
MEST
|
mesoderm specific transcript
|
3.26658
|
|
CHN1
|
chimerin 1
|
3.26034
|
|
CSK
|
c-src tyrosine kinase
|
3.09817
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.09794
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.03128
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.98377
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.86787
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.72651
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.68432
|
|
EPHB2
|
EPH receptor B2
|
2.60198
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.4769
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.46391
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.39842
|
|
SHC1
|
SHC (Src homology 2 domain containing) transforming protein 1
|
2.34315
|
|
MICALL1
|
MICAL-like 1
|
2.28136
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.19748
|
|
STXBP2
|
syntaxin binding protein 2
|
2.16903
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.14138
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-4.89021
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.80703
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.75627
|
|
VAT1
|
vesicle amine transport 1
|
-3.57736
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.5515
|
|
CCNB2
|
cyclin B2
|
-3.54791
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.467
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.45457
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.43363
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.2499
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.24047
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.17592
|
|
CDC20
|
cell division cycle 20
|
-3.09334
|
|
CAB39
|
calcium binding protein 39
|
-2.95787
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.86776
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-2.75039
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.60694
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
-2.54861
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.50819
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.41064
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.34537
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.20846
|
|
SLC18A2
|
solute carrier family 18 (vesicular monoamine transporter), member 2
|
-2.16032
|
|
CDC25B
|
cell division cycle 25B
|
-2.15123
|
|
SMG1
|
SMG1 phosphatidylinositol 3-kinase-related kinase
|
-2.14054
|
|
MGP
|
matrix Gla protein
|
-2.06029
|
|
TSPYL5
|
TSPY-like 5
|
-2.00261
|
