CRCGN010_HEPG2_24H:F04 Gene Set
Genes
49 genes differentially expressed following the CRCGN010_HEPG2_24H:F04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
6.31547
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
6.2667
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
5.70987
|
|
LCN2
|
lipocalin 2
|
4.61097
|
|
PRR15L
|
proline rich 15-like
|
4.30758
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.37995
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.3222
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.30657
|
|
CSK
|
c-src tyrosine kinase
|
3.30579
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.16254
|
|
CDC45
|
cell division cycle 45
|
3.14224
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.12501
|
|
NOTCH1
|
notch 1
|
2.94307
|
|
E2F2
|
E2F transcription factor 2
|
2.93632
|
|
UBE2L6
|
ubiquitin-conjugating enzyme E2L 6
|
2.68656
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.61871
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.5295
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.46866
|
|
MAMLD1
|
mastermind-like domain containing 1
|
2.45825
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
2.44467
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.42492
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.32436
|
|
GATA2
|
GATA binding protein 2
|
2.28223
|
|
H2BC12
|
H2B clustered histone 12
|
2.21531
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.19567
|
|
CHN1
|
chimerin 1
|
2.13505
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.12453
|
|
GPATCH8
|
G patch domain containing 8
|
2.09879
|
|
CCNF
|
cyclin F
|
2.01503
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.2832
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-4.75053
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-4.50036
|
|
TLR4
|
toll-like receptor 4
|
-4.47561
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.63874
|
|
HAT1
|
histone acetyltransferase 1
|
-3.58696
|
|
ZNF586
|
zinc finger protein 586
|
-3.55081
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.34782
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.19304
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.16034
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.07481
|
|
LDHD
|
lactate dehydrogenase D
|
-2.95216
|
|
CPSF4
|
cleavage and polyadenylation specific factor 4, 30kDa
|
-2.71331
|
|
RAI14
|
retinoic acid induced 14
|
-2.71236
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.67254
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.48735
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.46179
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.44353
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.40142
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
-2.10408
|
