CRCGN010_HEPG2_24H:F05 Gene Set
Genes
41 genes differentially expressed following the CRCGN010_HEPG2_24H:F05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
8.60848
|
|
CYCS
|
cytochrome c, somatic
|
7.2591
|
|
H2BC12
|
H2B clustered histone 12
|
6.02708
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.83361
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.60743
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
4.24264
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.17263
|
|
GADD45A
|
growth arrest and DNA-damage-inducible, alpha
|
3.95324
|
|
STAP2
|
signal transducing adaptor family member 2
|
3.92197
|
|
PRKCH
|
protein kinase C, eta
|
3.69861
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.65073
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.52641
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.35305
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.9937
|
|
GPATCH8
|
G patch domain containing 8
|
2.91518
|
|
CHEK2
|
checkpoint kinase 2
|
2.80048
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
2.41744
|
|
PRR15L
|
proline rich 15-like
|
2.35844
|
|
GATA2
|
GATA binding protein 2
|
2.11578
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.75574
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.90522
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.45627
|
|
CCNB2
|
cyclin B2
|
-4.437
|
|
LDHD
|
lactate dehydrogenase D
|
-4.28293
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-4.04077
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-4.03989
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-3.29242
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.19863
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.1434
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.02892
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.92139
|
|
FBXO7
|
F-box protein 7
|
-2.56243
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.32007
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.25631
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
-2.23066
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.20441
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.1828
|
|
HSD17B10
|
hydroxysteroid (17-beta) dehydrogenase 10
|
-2.17354
|
|
NQO1
|
NAD(P)H dehydrogenase, quinone 1
|
-2.06597
|
|
PROS1
|
protein S (alpha)
|
-2.04243
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.01124
|
