| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-nitrosoazocane 0.66 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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71 genes differentially expressed following the CRCGN010_HEPG2_24H:F06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYLK | myosin light chain kinase | 7.71398 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 6.28056 |
| LCN2 | lipocalin 2 | 5.39938 |
| STK10 | serine/threonine kinase 10 | 4.09809 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.0535 |
| LAGE3 | L antigen family, member 3 | 4.04565 |
| E2F2 | E2F transcription factor 2 | 3.97982 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.85874 |
| PRR15L | proline rich 15-like | 3.2607 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.16742 |
| GPATCH8 | G patch domain containing 8 | 3.0562 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.90527 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.80123 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.72363 |
| PMM2 | phosphomannomutase 2 | 2.61807 |
| LOC122526780 | uncharacterized LOC122526780 | 2.46958 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | 2.41576 |
| IQSEC3 | IQ motif and Sec7 domain 3 | 2.33298 |
| KIF11 | kinesin family member 11 | 2.30485 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.26066 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 2.20106 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 | 2.15308 |
| S100A1 | S100 calcium binding protein A1 | 2.14986 |
| TXNL4B | thioredoxin-like 4B | 2.13974 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.12254 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 2.11442 |
| TSC22D3 | TSC22 domain family, member 3 | 2.09323 |
| NNT | nicotinamide nucleotide transhydrogenase | 2.0825 |
| APOO | apolipoprotein O | 2.07186 |
| EVL | Enah/Vasp-like | 2.06687 |
| POU2F3 | POU class 2 homeobox 3 | 2.03503 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 2.00754 |
| TMEM45A | transmembrane protein 45A | 2.00493 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -10.0 |
| SLC35F2 | solute carrier family 35, member F2 | -5.99525 |
| VAT1 | vesicle amine transport 1 | -4.7402 |
| TUBB6 | tubulin, beta 6 class V | -4.54819 |
| DERA | deoxyribose-phosphate aldolase (putative) | -4.40751 |
| DSG2 | desmoglein 2 | -4.25937 |
| UGDH | UDP-glucose 6-dehydrogenase | -4.21725 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -3.86951 |
| ADI1 | acireductone dioxygenase 1 | -3.86269 |
| LDHD | lactate dehydrogenase D | -3.8279 |
| CCDC86 | coiled-coil domain containing 86 | -3.72221 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.67836 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -3.60098 |
| CDC20 | cell division cycle 20 | -3.43689 |
| TLR4 | toll-like receptor 4 | -3.40454 |
| TRIB3 | tribbles pseudokinase 3 | -3.16324 |
| FASTKD5 | FAST kinase domains 5 | -2.8771 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.73756 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -2.68546 |
| SNX11 | sorting nexin 11 | -2.63636 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.60673 |
| CCNB2 | cyclin B2 | -2.54992 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.54351 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B | -2.51336 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -2.48807 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.44429 |
| GNAS | GNAS complex locus | -2.34899 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.3047 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.20522 |
| YME1L1 | YME1-like 1 ATPase | -2.1585 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.14014 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -2.13505 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | -2.08596 |
| CHMP4B | charged multivesicular body protein 4B | -2.07168 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.05822 |
| TSPAN14 | tetraspanin 14 | -2.02957 |
| NGRN | neugrin, neurite outgrowth associated | -2.01562 |
| GLOD4 | glyoxalase domain containing 4 | -2.01217 |
