CRCGN010_HEPG2_24H:F08 Gene Set
Genes
54 genes differentially expressed following the CRCGN010_HEPG2_24H:F08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
6.76606
|
|
MAP7
|
microtubule-associated protein 7
|
6.65661
|
|
CHMP6
|
charged multivesicular body protein 6
|
5.19451
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.89637
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.76549
|
|
SATB1
|
SATB homeobox 1
|
4.67397
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.45554
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
4.02902
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.86345
|
|
EVL
|
Enah/Vasp-like
|
3.62064
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.39016
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.38718
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.31493
|
|
HDGFL3
|
HDGF like 3
|
3.28329
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.90286
|
|
PRR15L
|
proline rich 15-like
|
2.83445
|
|
CCNF
|
cyclin F
|
2.82238
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.80683
|
|
PMM2
|
phosphomannomutase 2
|
2.68358
|
|
CYCS
|
cytochrome c, somatic
|
2.6247
|
|
SHC1
|
SHC (Src homology 2 domain containing) transforming protein 1
|
2.56652
|
|
KLHL9
|
kelch-like family member 9
|
2.5338
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.5115
|
|
CHN1
|
chimerin 1
|
2.25652
|
|
SFTPB
|
surfactant protein B
|
2.18052
|
|
CCL21
|
chemokine (C-C motif) ligand 21
|
2.09308
|
|
GSK3B
|
glycogen synthase kinase 3 beta
|
2.09161
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.08801
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.04893
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-6.14299
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-5.88236
|
|
FASTKD5
|
FAST kinase domains 5
|
-5.55735
|
|
NUP85
|
nucleoporin 85kDa
|
-5.4081
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.95685
|
|
LDHD
|
lactate dehydrogenase D
|
-4.85339
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-4.74549
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.36531
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.11149
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.04026
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.63198
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.50019
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.23235
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.88251
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.82428
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.82225
|
|
GNAS
|
GNAS complex locus
|
-2.73742
|
|
CCNH
|
cyclin H
|
-2.52654
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.35065
|
|
SCCPDH
|
saccharopine dehydrogenase (putative)
|
-2.22998
|
|
TP53BP2
|
tumor protein p53 binding protein 2
|
-2.08537
|
|
ACSF2
|
acyl-CoA synthetase family member 2
|
-2.06202
|
|
HABP4
|
hyaluronan binding protein 4
|
-2.02235
|
|
CSK
|
c-src tyrosine kinase
|
-2.00451
|
|
TBCCD1
|
TBCC domain containing 1
|
-2.00148
|
