| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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83 genes differentially expressed following the CRCGN010_HEPG2_24H:F09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CCL2 | chemokine (C-C motif) ligand 2 | 8.43133 |
| AMDHD2 | amidohydrolase domain containing 2 | 7.13099 |
| NOTCH1 | notch 1 | 6.30949 |
| GSTZ1 | glutathione S-transferase zeta 1 | 5.99594 |
| CYCS | cytochrome c, somatic | 4.69804 |
| RXYLT1 | ribitol xylosyltransferase 1 | 4.39259 |
| DIPK1A | divergent protein kinase domain 1A | 3.9357 |
| JADE2 | jade family PHD finger 2 | 3.87252 |
| LSR | lipolysis stimulated lipoprotein receptor | 3.7851 |
| GPATCH8 | G patch domain containing 8 | 3.70405 |
| ADAM10 | ADAM metallopeptidase domain 10 | 3.69297 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 3.44385 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 3.37581 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.35182 |
| CHEK2 | checkpoint kinase 2 | 3.34782 |
| CHN1 | chimerin 1 | 3.29273 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.26559 |
| E2F2 | E2F transcription factor 2 | 3.25728 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.02378 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.9853 |
| LCN2 | lipocalin 2 | 2.9792 |
| STK10 | serine/threonine kinase 10 | 2.94849 |
| STIMATE | STIM activating enhancer | 2.75963 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.70333 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.66491 |
| NOSIP | nitric oxide synthase interacting protein | 2.58034 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 2.52782 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 2.51789 |
| UFM1 | ubiquitin-fold modifier 1 | 2.4864 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.36181 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 2.30128 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.23833 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.20834 |
| TECR | trans-2,3-enoyl-CoA reductase | 2.18757 |
| BAD | BCL2-associated agonist of cell death | 2.11555 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.09989 |
| ABHD6 | abhydrolase domain containing 6 | 2.07094 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | 2.05584 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 2.0327 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 2.01447 |
| ACOT7 | acyl-CoA thioesterase 7 | 2.01254 |
| MAP7 | microtubule-associated protein 7 | 2.00771 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -6.85082 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -6.73379 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -5.8116 |
| TLR4 | toll-like receptor 4 | -5.75373 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.64787 |
| GNAS | GNAS complex locus | -4.51103 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.39992 |
| LAP3 | leucine aminopeptidase 3 | -4.05186 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -3.8867 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -3.87626 |
| ACOT9 | acyl-CoA thioesterase 9 | -3.59915 |
| CCDC86 | coiled-coil domain containing 86 | -3.52788 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.48317 |
| LDHD | lactate dehydrogenase D | -3.38398 |
| FASTKD5 | FAST kinase domains 5 | -3.21458 |
| PCNA | proliferating cell nuclear antigen | -3.07371 |
| COG2 | component of oligomeric golgi complex 2 | -3.06108 |
| THAP11 | THAP domain containing 11 | -3.05242 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.02922 |
| GOLT1B | golgi transport 1B | -2.96399 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.9382 |
| PPOX | protoporphyrinogen oxidase | -2.91601 |
| ZNF274 | zinc finger protein 274 | -2.67495 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 | -2.5841 |
| CCNB2 | cyclin B2 | -2.53869 |
| TLCD3A | TLC domain containing 3A | -2.52469 |
| TCTN1 | tectonic family member 1 | -2.50308 |
| SLC35G2 | solute carrier family 35, member G2 | -2.45007 |
| HPS6 | Hermansky-Pudlak syndrome 6 | -2.43888 |
| CHMP4B | charged multivesicular body protein 4B | -2.35985 |
| CAB39L | calcium binding protein 39-like | -2.22838 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.19642 |
| RHOBTB1 | Rho-related BTB domain containing 1 | -2.19496 |
| POLR3F | polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa | -2.17972 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.16979 |
| RMDN3 | regulator of microtubule dynamics 3 | -2.13789 |
| NEK11 | NIMA-related kinase 11 | -2.11248 |
| NALF2 | NALCN channel auxiliary factor 2 | -2.0903 |
| CHPF2 | chondroitin polymerizing factor 2 | -2.06973 |
| MRPL9 | mitochondrial ribosomal protein L9 | -2.02817 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -2.01022 |
