CRCGN010_HEPG2_24H:F11 Gene Set
Genes
49 genes differentially expressed following the CRCGN010_HEPG2_24H:F11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
6.88879
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.58989
|
|
MAP7
|
microtubule-associated protein 7
|
5.92421
|
|
MAMLD1
|
mastermind-like domain containing 1
|
5.41732
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
5.16586
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
5.15962
|
|
UBQLN2
|
ubiquilin 2
|
5.08477
|
|
RPL39L
|
ribosomal protein L39-like
|
5.06147
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.7907
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.6355
|
|
CHN1
|
chimerin 1
|
4.46523
|
|
LOC122526780
|
uncharacterized LOC122526780
|
4.31877
|
|
PCDHB11
|
protocadherin beta 11
|
3.46299
|
|
EPHA3
|
EPH receptor A3
|
3.25472
|
|
TBXA2R
|
thromboxane A2 receptor
|
3.21503
|
|
JADE2
|
jade family PHD finger 2
|
3.05383
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.76446
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.65448
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.50043
|
|
GPATCH8
|
G patch domain containing 8
|
2.49215
|
|
MAPK3
|
mitogen-activated protein kinase 3
|
2.17001
|
|
OSBP2
|
oxysterol binding protein 2
|
2.15133
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.12078
|
|
MEST
|
mesoderm specific transcript
|
2.09192
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-9.67768
|
|
CCNB1
|
cyclin B1
|
-6.1976
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-5.61708
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.87627
|
|
ISOC1
|
isochorismatase domain containing 1
|
-4.78948
|
|
CTSD
|
cathepsin D
|
-4.46054
|
|
GNAS
|
GNAS complex locus
|
-3.57445
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.12179
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.04007
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.7558
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.68354
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.6705
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.65278
|
|
USP6NL
|
USP6 N-terminal like
|
-2.6129
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.56326
|
|
ZNF586
|
zinc finger protein 586
|
-2.55316
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.47133
|
|
GOLT1B
|
golgi transport 1B
|
-2.38992
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.33935
|
|
SNX11
|
sorting nexin 11
|
-2.31178
|
|
VPS37C
|
vacuolar protein sorting 37 homolog C (S. cerevisiae)
|
-2.27032
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.24805
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.19393
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.13913
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.04626
|
