CRCGN010_HEPG2_24H:F13 Gene Set
Genes
57 genes differentially expressed following the CRCGN010_HEPG2_24H:F13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
10.0
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
8.45001
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
4.74067
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.55775
|
|
UBQLN2
|
ubiquilin 2
|
4.50931
|
|
CCNF
|
cyclin F
|
4.27022
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.07834
|
|
NOTCH1
|
notch 1
|
4.06673
|
|
MAP7
|
microtubule-associated protein 7
|
3.44944
|
|
HDGFL3
|
HDGF like 3
|
3.20478
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
3.16326
|
|
GATA3
|
GATA binding protein 3
|
3.02173
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.93071
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.91932
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.87179
|
|
SFTPB
|
surfactant protein B
|
2.77136
|
|
SDC1
|
syndecan 1
|
2.4926
|
|
SHB
|
Src homology 2 domain containing adaptor protein B
|
2.47953
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.28731
|
|
CXCL3
|
chemokine (C-X-C motif) ligand 3
|
2.25942
|
|
HECTD4
|
HECT domain containing E3 ubiquitin protein ligase 4
|
2.21015
|
|
CHN1
|
chimerin 1
|
2.19816
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.18387
|
|
RIC8B
|
RIC8 guanine nucleotide exchange factor B
|
2.12955
|
|
HSPA8
|
heat shock 70kDa protein 8
|
2.09017
|
|
TRIM13
|
tripartite motif containing 13
|
2.03841
|
|
PRKAG1
|
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
|
2.03408
|
|
SMC6
|
structural maintenance of chromosomes 6
|
2.03061
|
|
TMED5
|
transmembrane emp24 protein transport domain containing 5
|
2.01413
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-8.8763
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-8.65554
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-8.57862
|
|
CCNB2
|
cyclin B2
|
-4.82752
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.62637
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.55258
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.44044
|
|
THAP11
|
THAP domain containing 11
|
-4.35972
|
|
DSG2
|
desmoglein 2
|
-4.27642
|
|
LDHD
|
lactate dehydrogenase D
|
-4.22641
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-4.13985
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.91405
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.60024
|
|
GNAS
|
GNAS complex locus
|
-3.57041
|
|
CCNB1
|
cyclin B1
|
-3.40884
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.33304
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.24768
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.9301
|
|
SNX11
|
sorting nexin 11
|
-2.67781
|
|
CD320
|
CD320 molecule
|
-2.57165
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.54324
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.41137
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.35167
|
|
TACR2
|
tachykinin receptor 2
|
-2.27605
|
|
EIF4EBP3
|
eukaryotic translation initiation factor 4E binding protein 3
|
-2.1271
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.068
|
|
COL9A2
|
collagen, type IX, alpha 2
|
-2.02898
|
|
CTSV
|
cathepsin V
|
-2.01927
|
