CRCGN010_HEPG2_24H:F14 Gene Set
Genes
55 genes differentially expressed following the CRCGN010_HEPG2_24H:F14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
7.06493
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.77166
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
4.51888
|
|
UBQLN2
|
ubiquilin 2
|
4.419
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.2725
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
4.17347
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.90174
|
|
NOTCH1
|
notch 1
|
3.83406
|
|
JADE2
|
jade family PHD finger 2
|
3.69222
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
3.06435
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
3.01202
|
|
SATB1
|
SATB homeobox 1
|
2.95518
|
|
STIMATE
|
STIM activating enhancer
|
2.93285
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.93165
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.92984
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.91926
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
2.81146
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.69927
|
|
GATA2
|
GATA binding protein 2
|
2.68505
|
|
CCNF
|
cyclin F
|
2.5589
|
|
CBR3
|
carbonyl reductase 3
|
2.52766
|
|
PLS1
|
plastin 1
|
2.4733
|
|
STK10
|
serine/threonine kinase 10
|
2.39871
|
|
MAP7
|
microtubule-associated protein 7
|
2.33374
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.22331
|
|
NFE2
|
nuclear factor, erythroid 2
|
2.21034
|
|
STX10
|
syntaxin 10
|
2.07899
|
|
GPATCH3
|
G patch domain containing 3
|
2.06817
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.03255
|
|
CHSY1
|
chondroitin sulfate synthase 1
|
2.00219
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-10.0
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-7.32115
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-5.47316
|
|
GNAS
|
GNAS complex locus
|
-4.67868
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.32164
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.19872
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.09361
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.84162
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-3.75087
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.02936
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.95188
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.78082
|
|
LDHD
|
lactate dehydrogenase D
|
-2.70106
|
|
CAB39
|
calcium binding protein 39
|
-2.68991
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.58809
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.57123
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.56191
|
|
RNF167
|
ring finger protein 167
|
-2.56068
|
|
VAT1
|
vesicle amine transport 1
|
-2.38627
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-2.18151
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.14675
|
|
MTHFD1
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
|
-2.13186
|
|
TBCB
|
tubulin folding cofactor B
|
-2.12397
|
|
CDC20
|
cell division cycle 20
|
-2.11766
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.00659
|
