CRCGN010_HEPG2_24H:F15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dimethylformamide 10.65 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

76 genes differentially expressed following the CRCGN010_HEPG2_24H:F15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PNKP polynucleotide kinase 3'-phosphatase 7.40616
PPARG peroxisome proliferator-activated receptor gamma 6.3093
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.84169
NOTCH1 notch 1 5.54549
ADGRE5 adhesion G protein-coupled receptor E5 4.16433
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 4.06965
CRTAP cartilage associated protein 3.78525
NOSIP nitric oxide synthase interacting protein 3.67579
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.32094
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.2392
ZNF589 zinc finger protein 589 3.12536
GSTZ1 glutathione S-transferase zeta 1 3.08311
MSRA methionine sulfoxide reductase A 2.97829
MAP7 microtubule-associated protein 7 2.86037
TIAM1 T-cell lymphoma invasion and metastasis 1 2.76105
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.72979
PLSCR3 phospholipid scramblase 3 2.64267
ERCC2 excision repair cross-complementation group 2 2.49594
TXLNA taxilin alpha 2.48914
GATA3 GATA binding protein 3 2.42289
CEMIP2 cell migration inducing hyaluronidase 2 2.42071
CHN1 chimerin 1 2.38853
MTERF3 mitochondrial transcription termination factor 3 2.35779
IDE insulin-degrading enzyme 2.29145
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.28799
PDLIM1 PDZ and LIM domain 1 2.28073
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.15939
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.12016
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 2.09455
CHMP6 charged multivesicular body protein 6 2.00207

decreased expression

Symbol Name Standardized Value
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -6.38618
OXA1L oxidase (cytochrome c) assembly 1-like -6.28959
LDHD lactate dehydrogenase D -5.92991
ZNF586 zinc finger protein 586 -5.65894
TM9SF3 transmembrane 9 superfamily member 3 -4.37149
NRIP1 nuclear receptor interacting protein 1 -4.14032
MRPS2 mitochondrial ribosomal protein S2 -3.77006
FGFR4 fibroblast growth factor receptor 4 -3.72933
GNAS GNAS complex locus -3.72926
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -3.4793
RPN1 ribophorin I -3.44432
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.43609
TUBB6 tubulin, beta 6 class V -3.40695
YME1L1 YME1-like 1 ATPase -3.33453
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -3.11599
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.09169
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.02003
PRR11 proline rich 11 -2.96792
CCNB2 cyclin B2 -2.95941
DNM1L dynamin 1-like -2.84567
RNF167 ring finger protein 167 -2.67682
COG7 component of oligomeric golgi complex 7 -2.64921
TLR4 toll-like receptor 4 -2.47752
PCNA proliferating cell nuclear antigen -2.44068
ERC2 ELKS/RAB6-interacting/CAST family member 2 -2.40437
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.40352
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.40304
ADI1 acireductone dioxygenase 1 -2.26496
ZNF669 zinc finger protein 669 -2.23764
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -2.19511
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -2.19458
PCCB propionyl CoA carboxylase, beta polypeptide -2.18573
KRT83 keratin 83, type II -2.16951
HAUS2 HAUS augmin-like complex, subunit 2 -2.1667
NGRN neugrin, neurite outgrowth associated -2.15908
ITGB1BP1 integrin beta 1 binding protein 1 -2.15229
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome -2.12699
CST8 cystatin 8 (cystatin-related epididymal specific) -2.12532
THAP11 THAP domain containing 11 -2.11714
ERN2 endoplasmic reticulum to nucleus signaling 2 -2.10316
STMN1 stathmin 1 -2.06734
TOMM70 translocase of outer mitochondrial membrane 70 -2.05543
NONO non-POU domain containing, octamer-binding -2.05509
KRT32 keratin 32, type I -2.0345
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) -2.03189
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -2.01093