| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dimethylformamide 2.66 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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79 genes differentially expressed following the CRCGN010_HEPG2_24H:F17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| E2F2 | E2F transcription factor 2 | 10.0 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 9.33085 |
| MYLK | myosin light chain kinase | 5.24515 |
| CHEK2 | checkpoint kinase 2 | 5.17355 |
| ATP11B | ATPase, class VI, type 11B | 4.9989 |
| ANO10 | anoctamin 10 | 4.70146 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.5275 |
| CHMP6 | charged multivesicular body protein 6 | 4.49054 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 4.45635 |
| PLS1 | plastin 1 | 4.12142 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.03528 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.76087 |
| STK10 | serine/threonine kinase 10 | 3.70131 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.46248 |
| HSPA1A | heat shock 70kDa protein 1A | 3.36322 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 2.95347 |
| CCNF | cyclin F | 2.8378 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.67108 |
| SNRPD3 | small nuclear ribonucleoprotein D3 polypeptide 18kDa | 2.6274 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.62018 |
| EVL | Enah/Vasp-like | 2.52498 |
| VGLL4 | vestigial-like family member 4 | 2.5031 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.46694 |
| TEX10 | testis expressed 10 | 2.46636 |
| MRPL30 | mitochondrial ribosomal protein L30 | 2.22949 |
| SAA4 | serum amyloid A4, constitutive | 2.22763 |
| VNN1 | vanin 1 | 2.19767 |
| GLDC | glycine dehydrogenase (decarboxylating) | 2.17773 |
| PITX2 | paired-like homeodomain 2 | 2.17319 |
| CHSY1 | chondroitin sulfate synthase 1 | 2.13016 |
| SAA2 | serum amyloid A2 | 2.1295 |
| DVL3 | dishevelled segment polarity protein 3 | 2.11585 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 2.09924 |
| ADAM10 | ADAM metallopeptidase domain 10 | 2.07892 |
| DHODH | dihydroorotate dehydrogenase (quinone) | 2.07849 |
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | 2.0491 |
| GRB10 | growth factor receptor-bound protein 10 | 2.04503 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 2.03313 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 2.00156 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -9.12757 |
| GNAS | GNAS complex locus | -6.29923 |
| KDM3A | lysine (K)-specific demethylase 3A | -5.44174 |
| LDHD | lactate dehydrogenase D | -5.22827 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -5.03833 |
| ZNF586 | zinc finger protein 586 | -5.01375 |
| UGDH | UDP-glucose 6-dehydrogenase | -4.71983 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.67615 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.66528 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.65341 |
| CDC20 | cell division cycle 20 | -4.6154 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -4.50304 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -4.49249 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -4.46061 |
| RAI14 | retinoic acid induced 14 | -4.06885 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -3.93527 |
| RHEB | Ras homolog enriched in brain | -3.57772 |
| COG4 | component of oligomeric golgi complex 4 | -3.57647 |
| FBXO7 | F-box protein 7 | -3.27328 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -3.16456 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.89884 |
| CUL1 | cullin 1 | -2.80884 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -2.54773 |
| PEG10 | paternally expressed 10 | -2.53569 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.45779 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.40431 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -2.27511 |
| ZW10 | zw10 kinetochore protein | -2.2638 |
| ADI1 | acireductone dioxygenase 1 | -2.24881 |
| RFPL3 | ret finger protein-like 3 | -2.22151 |
| LRRK1 | leucine-rich repeat kinase 1 | -2.17418 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -2.12983 |
| STAP1 | signal transducing adaptor family member 1 | -2.12525 |
| CLIC5 | chloride intracellular channel 5 | -2.10072 |
| ZNF282 | zinc finger protein 282 | -2.06439 |
| TREML2 | triggering receptor expressed on myeloid cells-like 2 | -2.05975 |
| FKBP4 | FK506 binding protein 4, 59kDa | -2.03886 |
| CD40LG | CD40 ligand | -2.03701 |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 | -2.03412 |
| FTSJ1 | FtsJ RNA methyltransferase homolog 1 (E. coli) | -2.02703 |
