CRCGN010_HEPG2_24H:F18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dimethylformamide 1.33 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

63 genes differentially expressed following the CRCGN010_HEPG2_24H:F18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 8.01703
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 5.40605
CHN1 chimerin 1 4.48825
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.10178
CIAO3 cytosolic iron-sulfur assembly component 3 4.06394
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.87791
GPER1 G protein-coupled estrogen receptor 1 3.85456
LYN LYN proto-oncogene, Src family tyrosine kinase 3.74143
CARMIL1 capping protein regulator and myosin 1 linker 1 3.51758
C2CD2 C2 calcium-dependent domain containing 2 3.48975
LPAR2 lysophosphatidic acid receptor 2 3.42332
HOXA10 homeobox A10 3.38973
HDGFL3 HDGF like 3 3.12307
PEX11A peroxisomal biogenesis factor 11 alpha 2.86434
RXYLT1 ribitol xylosyltransferase 1 2.78011
ADRB2 adrenoceptor beta 2, surface 2.75226
DIPK1A divergent protein kinase domain 1A 2.67322
TREM1 triggering receptor expressed on myeloid cells 1 2.65389
CCNF cyclin F 2.62332
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.55995
HSPA8 heat shock 70kDa protein 8 2.5011
JADE2 jade family PHD finger 2 2.47662
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.43214
DYNLT3 dynein, light chain, Tctex-type 3 2.42891
KIF5C kinesin family member 5C 2.40878
PFKL phosphofructokinase, liver 2.38782
DIXDC1 DIX domain containing 1 2.32482
EPN2 epsin 2 2.25583
ANO1 anoctamin 1, calcium activated chloride channel 2.17853
RAB4A RAB4A, member RAS oncogene family 2.17837
GATA2 GATA binding protein 2 2.11845
LCN2 lipocalin 2 2.10423
COPS7A COP9 signalosome subunit 7A 2.10027
CDC45 cell division cycle 45 2.06997
GARRE1 granule associated Rac and RHOG effector 1 2.04691
GNA14 guanine nucleotide binding protein (G protein), alpha 14 2.03829
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.02336

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -8.07652
OXA1L oxidase (cytochrome c) assembly 1-like -6.69731
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -6.38352
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -6.12974
ADI1 acireductone dioxygenase 1 -6.10755
PCNA proliferating cell nuclear antigen -5.71765
GNAS GNAS complex locus -5.27113
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.98841
MRPS2 mitochondrial ribosomal protein S2 -4.84757
CASP7 caspase 7, apoptosis-related cysteine peptidase -4.62382
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.36714
MAPK13 mitogen-activated protein kinase 13 -3.37812
NISCH nischarin -3.35801
TM9SF3 transmembrane 9 superfamily member 3 -2.97655
UGDH UDP-glucose 6-dehydrogenase -2.90039
SLC35F2 solute carrier family 35, member F2 -2.75382
TCTN1 tectonic family member 1 -2.58916
GLB1L galactosidase, beta 1-like -2.46212
PEG10 paternally expressed 10 -2.46068
KDM3A lysine (K)-specific demethylase 3A -2.3381
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.3335
PLA2G15 phospholipase A2, group XV -2.21555
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B -2.20082
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -2.1892
TXNDC9 thioredoxin domain containing 9 -2.1066
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.03597