| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dimethylformamide 1.33 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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63 genes differentially expressed following the CRCGN010_HEPG2_24H:F18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 8.01703 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 5.40605 |
| CHN1 | chimerin 1 | 4.48825 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.10178 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.06394 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.87791 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.85456 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 3.74143 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.51758 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.48975 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.42332 |
| HOXA10 | homeobox A10 | 3.38973 |
| HDGFL3 | HDGF like 3 | 3.12307 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.86434 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.78011 |
| ADRB2 | adrenoceptor beta 2, surface | 2.75226 |
| DIPK1A | divergent protein kinase domain 1A | 2.67322 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.65389 |
| CCNF | cyclin F | 2.62332 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.55995 |
| HSPA8 | heat shock 70kDa protein 8 | 2.5011 |
| JADE2 | jade family PHD finger 2 | 2.47662 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.43214 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.42891 |
| KIF5C | kinesin family member 5C | 2.40878 |
| PFKL | phosphofructokinase, liver | 2.38782 |
| DIXDC1 | DIX domain containing 1 | 2.32482 |
| EPN2 | epsin 2 | 2.25583 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.17853 |
| RAB4A | RAB4A, member RAS oncogene family | 2.17837 |
| GATA2 | GATA binding protein 2 | 2.11845 |
| LCN2 | lipocalin 2 | 2.10423 |
| COPS7A | COP9 signalosome subunit 7A | 2.10027 |
| CDC45 | cell division cycle 45 | 2.06997 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.04691 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 | 2.03829 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 2.02336 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -8.07652 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.69731 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.38352 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -6.12974 |
| ADI1 | acireductone dioxygenase 1 | -6.10755 |
| PCNA | proliferating cell nuclear antigen | -5.71765 |
| GNAS | GNAS complex locus | -5.27113 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.98841 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.84757 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.62382 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.36714 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.37812 |
| NISCH | nischarin | -3.35801 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.97655 |
| UGDH | UDP-glucose 6-dehydrogenase | -2.90039 |
| SLC35F2 | solute carrier family 35, member F2 | -2.75382 |
| TCTN1 | tectonic family member 1 | -2.58916 |
| GLB1L | galactosidase, beta 1-like | -2.46212 |
| PEG10 | paternally expressed 10 | -2.46068 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.3381 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.3335 |
| PLA2G15 | phospholipase A2, group XV | -2.21555 |
| DDX19B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B | -2.20082 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | -2.1892 |
| TXNDC9 | thioredoxin domain containing 9 | -2.1066 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -2.03597 |