CRCGN010_HEPG2_24H:F19 Gene Set
Genes
46 genes differentially expressed following the CRCGN010_HEPG2_24H:F19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
4.75614
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.47069
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.28993
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.69833
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.69663
|
|
CSK
|
c-src tyrosine kinase
|
2.51513
|
|
NOTCH1
|
notch 1
|
2.48702
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.42936
|
|
THUMPD2
|
THUMP domain containing 2
|
2.41638
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.38861
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.35254
|
|
POLG2
|
polymerase (DNA directed), gamma 2, accessory subunit
|
2.31474
|
|
EGF
|
epidermal growth factor
|
2.24725
|
|
TAF2
|
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
|
2.19029
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.17093
|
|
AZIN2
|
antizyme inhibitor 2
|
2.07269
|
|
TNFRSF1A
|
tumor necrosis factor receptor superfamily, member 1A
|
2.05999
|
|
LCN2
|
lipocalin 2
|
2.01377
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PLK1
|
polo-like kinase 1
|
-7.41341
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-7.0542
|
|
CCNB2
|
cyclin B2
|
-6.93372
|
|
GNAS
|
GNAS complex locus
|
-5.07412
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.8386
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.72132
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-4.7173
|
|
CD58
|
CD58 molecule
|
-4.65919
|
|
LDHD
|
lactate dehydrogenase D
|
-4.59083
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.40759
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.27463
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.20053
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.11815
|
|
DNM1L
|
dynamin 1-like
|
-4.01562
|
|
TLR4
|
toll-like receptor 4
|
-3.78582
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.11327
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.02584
|
|
CAB39
|
calcium binding protein 39
|
-2.94216
|
|
CDC20
|
cell division cycle 20
|
-2.83133
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-2.81367
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.47101
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.34275
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.20025
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.1789
|
|
LGI1
|
leucine-rich, glioma inactivated 1
|
-2.17764
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.08026
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.07811
|
|
MRPL37
|
mitochondrial ribosomal protein L37
|
-2.00361
|
