CRCGN010_HEPG2_24H:F20 Gene Set
Genes
51 genes differentially expressed following the CRCGN010_HEPG2_24H:F20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.65627
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.56231
|
|
STAP2
|
signal transducing adaptor family member 2
|
4.50977
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
4.42454
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.36673
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.30561
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.25672
|
|
TEX10
|
testis expressed 10
|
3.68487
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.62662
|
|
SFTPB
|
surfactant protein B
|
3.61498
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.58774
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.31049
|
|
EVL
|
Enah/Vasp-like
|
2.9882
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.98463
|
|
BAX
|
BCL2-associated X protein
|
2.9578
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.89188
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.68228
|
|
H2BC12
|
H2B clustered histone 12
|
2.64514
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
2.51519
|
|
GATA2
|
GATA binding protein 2
|
2.49835
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
2.45079
|
|
CHN1
|
chimerin 1
|
2.24859
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.1988
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.1485
|
|
AHSG
|
alpha-2-HS-glycoprotein
|
2.12165
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.11196
|
|
HMOX1
|
heme oxygenase 1
|
2.04112
|
|
SAE1
|
SUMO1 activating enzyme subunit 1
|
2.03248
|
|
APOA2
|
apolipoprotein A-II
|
2.00208
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-8.96614
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-5.3219
|
|
LDHD
|
lactate dehydrogenase D
|
-4.85073
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-4.6707
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-4.5189
|
|
VAT1
|
vesicle amine transport 1
|
-4.45357
|
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
-4.4073
|
|
TLR4
|
toll-like receptor 4
|
-4.29985
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.1262
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.99571
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.77054
|
|
WDR7
|
WD repeat domain 7
|
-3.41572
|
|
RNF167
|
ring finger protein 167
|
-3.06134
|
|
HMG20B
|
high mobility group 20B
|
-2.80575
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.6776
|
|
CUTA
|
cutA divalent cation tolerance homolog (E. coli)
|
-2.46929
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-2.42101
|
|
TMEM39B
|
transmembrane protein 39B
|
-2.21809
|
|
GDF9
|
growth differentiation factor 9
|
-2.16855
|
|
SLC22A2
|
solute carrier family 22 (organic cation transporter), member 2
|
-2.15565
|
|
TMEM260
|
transmembrane protein 260
|
-2.04735
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.01186
|
