CRCGN010_HEPG2_24H:F22 Gene Set
Genes
34 genes differentially expressed following the CRCGN010_HEPG2_24H:F22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
6.57651
|
|
PRKCH
|
protein kinase C, eta
|
4.77965
|
|
PRR15L
|
proline rich 15-like
|
4.45691
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.97066
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.50402
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
3.22081
|
|
MAP7
|
microtubule-associated protein 7
|
3.18459
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.10018
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.97015
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.88254
|
|
PLS1
|
plastin 1
|
2.60823
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.55331
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.47972
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.42412
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.40937
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.34059
|
|
MEST
|
mesoderm specific transcript
|
2.28318
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.19206
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.15743
|
|
GNAS
|
GNAS complex locus
|
-4.24053
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.84091
|
|
TMCO1
|
transmembrane and coiled-coil domains 1
|
-3.83688
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.81031
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.76059
|
|
LDHD
|
lactate dehydrogenase D
|
-3.49571
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.43227
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-3.29067
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.91028
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.66838
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.64772
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.62708
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.23335
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.22879
|
|
CCNB1
|
cyclin B1
|
-2.05581
|
