CRCGN010_HEPG2_24H:F23 Gene Set
Genes
50 genes differentially expressed following the CRCGN010_HEPG2_24H:F23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AMDHD2
|
amidohydrolase domain containing 2
|
5.23133
|
|
CYCS
|
cytochrome c, somatic
|
5.0955
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
5.00581
|
|
LCN2
|
lipocalin 2
|
5.0
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.41075
|
|
EPN2
|
epsin 2
|
3.82391
|
|
CHN1
|
chimerin 1
|
3.5657
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
3.53379
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.49687
|
|
EVL
|
Enah/Vasp-like
|
3.13
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.86508
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.76817
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
2.72376
|
|
KLHL21
|
kelch-like family member 21
|
2.71496
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.64625
|
|
GPATCH8
|
G patch domain containing 8
|
2.64351
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.53849
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.51393
|
|
ZNF589
|
zinc finger protein 589
|
2.37032
|
|
GATA3
|
GATA binding protein 3
|
2.31793
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.31535
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.30792
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.20727
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.17716
|
|
EGF
|
epidermal growth factor
|
2.04893
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
FASTKD5
|
FAST kinase domains 5
|
-4.91271
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-4.849
|
|
TLR4
|
toll-like receptor 4
|
-3.79141
|
|
FDFT1
|
farnesyl-diphosphate farnesyltransferase 1
|
-3.51205
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.24164
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.10912
|
|
HMG20B
|
high mobility group 20B
|
-2.97247
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.72657
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.70101
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
-2.61478
|
|
CDC20
|
cell division cycle 20
|
-2.5806
|
|
ZW10
|
zw10 kinetochore protein
|
-2.5517
|
|
CD320
|
CD320 molecule
|
-2.52568
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.52167
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.51737
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.47049
|
|
NUP93
|
nucleoporin 93kDa
|
-2.43166
|
|
VAT1
|
vesicle amine transport 1
|
-2.40777
|
|
LDHD
|
lactate dehydrogenase D
|
-2.31682
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.16856
|
|
SLC4A1AP
|
solute carrier family 4 (anion exchanger), member 1, adaptor protein
|
-2.16068
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.15379
|
|
CCNB2
|
cyclin B2
|
-2.12905
|
|
KLHL25
|
kelch-like family member 25
|
-2.00804
|
|
UGT2B15
|
UDP glucuronosyltransferase 2 family, polypeptide B15
|
-2.00248
|
