CRCGN010_HEPG2_24H:G06 Gene Set
Genes
53 genes differentially expressed following the CRCGN010_HEPG2_24H:G06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GSTZ1
|
glutathione S-transferase zeta 1
|
6.70365
|
|
CSK
|
c-src tyrosine kinase
|
4.30349
|
|
E2F2
|
E2F transcription factor 2
|
4.15135
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
3.98595
|
|
HEBP1
|
heme binding protein 1
|
3.89739
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.79321
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.73553
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.2771
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.26983
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.15032
|
|
HOXA10
|
homeobox A10
|
3.11264
|
|
TRIM13
|
tripartite motif containing 13
|
2.77647
|
|
CHAC1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
2.77148
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.69942
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.48697
|
|
JADE2
|
jade family PHD finger 2
|
2.31436
|
|
NUCB2
|
nucleobindin 2
|
2.27391
|
|
ZNF589
|
zinc finger protein 589
|
2.27039
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.24721
|
|
MBNL2
|
muscleblind-like splicing regulator 2
|
2.24651
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.23201
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.19873
|
|
SQOR
|
sulfide quinone oxidoreductase
|
2.16981
|
|
PTK2
|
protein tyrosine kinase 2
|
2.14746
|
|
CTNNAL1
|
catenin (cadherin-associated protein), alpha-like 1
|
2.11746
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.02839
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-10.0
|
|
LDHD
|
lactate dehydrogenase D
|
-5.71612
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-4.39998
|
|
DSG2
|
desmoglein 2
|
-4.39064
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-3.86943
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.83805
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.60485
|
|
TLR4
|
toll-like receptor 4
|
-3.55436
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.55183
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.48674
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.38732
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.34467
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.32696
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.19721
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.11921
|
|
WASHC4
|
WASH complex subunit 4
|
-2.82827
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.80348
|
|
ZNF586
|
zinc finger protein 586
|
-2.67384
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.66171
|
|
GNAS
|
GNAS complex locus
|
-2.5619
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
-2.55782
|
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2
|
-2.42331
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-2.25913
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.22427
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.18374
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.14984
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.02846
|
