| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | phenyl-b-naphthylamine 9.95 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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64 genes differentially expressed following the CRCGN010_HEPG2_24H:G09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 5.47241 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 4.96491 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.61874 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.53071 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 4.47736 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 4.41294 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.37855 |
| CHMP6 | charged multivesicular body protein 6 | 4.3558 |
| GATA3 | GATA binding protein 3 | 3.23867 |
| HMOX1 | heme oxygenase 1 | 3.21894 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.14606 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 3.0435 |
| KLHL9 | kelch-like family member 9 | 3.04072 |
| CSK | c-src tyrosine kinase | 2.91585 |
| EVL | Enah/Vasp-like | 2.8024 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.78132 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.72372 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.63414 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 2.59182 |
| ZNF589 | zinc finger protein 589 | 2.52788 |
| TBP | TATA box binding protein | 2.51615 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.46566 |
| HSPA8 | heat shock 70kDa protein 8 | 2.45313 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.40577 |
| PARP2 | poly (ADP-ribose) polymerase 2 | 2.39302 |
| TXNRD1 | thioredoxin reductase 1 | 2.37752 |
| MAMLD1 | mastermind-like domain containing 1 | 2.34587 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.33938 |
| DIPK1A | divergent protein kinase domain 1A | 2.2699 |
| FZD7 | frizzled class receptor 7 | 2.25346 |
| COQ3 | coenzyme Q3 methyltransferase | 2.21293 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.19044 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.14305 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FAIM | Fas apoptotic inhibitory molecule | -4.96906 |
| GNAS | GNAS complex locus | -4.8149 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.72101 |
| NUP85 | nucleoporin 85kDa | -4.54804 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -4.46313 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.16438 |
| COG2 | component of oligomeric golgi complex 2 | -4.01274 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.97873 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.31755 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -3.18101 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.15927 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.09296 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -2.87707 |
| VDAC1 | voltage-dependent anion channel 1 | -2.87354 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -2.86976 |
| FASTKD5 | FAST kinase domains 5 | -2.85746 |
| CD320 | CD320 molecule | -2.82948 |
| SLC35F2 | solute carrier family 35, member F2 | -2.75742 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.5733 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.46549 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.44593 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.39619 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.35727 |
| CCDC86 | coiled-coil domain containing 86 | -2.35676 |
| CCNB2 | cyclin B2 | -2.34986 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | -2.33162 |
| ATP5PD | ATP synthase peripheral stalk subunit d | -2.33077 |
| ADRM1 | adhesion regulating molecule 1 | -2.09741 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -2.05961 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.05666 |
| MRPL58 | mitochondrial ribosomal protein L58 | -2.03113 |
