CRCGN010_HEPG2_24H:G10 Gene Set
Genes
60 genes differentially expressed following the CRCGN010_HEPG2_24H:G10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
8.1925
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
5.13754
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
5.13408
|
|
UBQLN2
|
ubiquilin 2
|
5.11743
|
|
KLHL9
|
kelch-like family member 9
|
4.91724
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.40749
|
|
CCNF
|
cyclin F
|
4.39159
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.36222
|
|
CYCS
|
cytochrome c, somatic
|
4.35118
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
4.07167
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.7696
|
|
MAP7
|
microtubule-associated protein 7
|
3.5983
|
|
HDGFL3
|
HDGF like 3
|
3.42131
|
|
MICALL1
|
MICAL-like 1
|
3.27453
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.25882
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.99817
|
|
STIMATE
|
STIM activating enhancer
|
2.96003
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.89922
|
|
PPIE
|
peptidylprolyl isomerase E (cyclophilin E)
|
2.84509
|
|
GATA3
|
GATA binding protein 3
|
2.8173
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.74778
|
|
GPATCH8
|
G patch domain containing 8
|
2.56671
|
|
NENF
|
neudesin neurotrophic factor
|
2.33595
|
|
PEPD
|
peptidase D
|
2.22324
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.1067
|
|
GOLPH3L
|
golgi phosphoprotein 3-like
|
2.10434
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.08811
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.08368
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.07983
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
2.04134
|
|
SARS2
|
seryl-tRNA synthetase 2, mitochondrial
|
2.00856
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-8.98202
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.71021
|
|
GOLT1B
|
golgi transport 1B
|
-4.76826
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-4.62128
|
|
ZNF586
|
zinc finger protein 586
|
-4.42992
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.26974
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.24534
|
|
CCNB1
|
cyclin B1
|
-4.20276
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-4.17509
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.98775
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.95247
|
|
CCNB2
|
cyclin B2
|
-3.69628
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-3.67002
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.43258
|
|
GNAS
|
GNAS complex locus
|
-3.37503
|
|
USP6NL
|
USP6 N-terminal like
|
-2.80535
|
|
TMEM97
|
transmembrane protein 97
|
-2.73406
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.705
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.65176
|
|
CD58
|
CD58 molecule
|
-2.50804
|
|
ATP6V0E2
|
ATPase, H+ transporting V0 subunit e2
|
-2.46885
|
|
RHEB
|
Ras homolog enriched in brain
|
-2.26893
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.26674
|
|
RPS5
|
ribosomal protein S5
|
-2.2053
|
|
REPIN1
|
replication initiator 1
|
-2.19376
|
|
CCT8
|
chaperonin containing TCP1, subunit 8 (theta)
|
-2.13138
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.08496
|
|
MYD88
|
myeloid differentiation primary response 88
|
-2.04473
|
|
CHPF2
|
chondroitin polymerizing factor 2
|
-2.01155
|
