| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | phenyl-b-naphthylamine 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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59 genes differentially expressed following the CRCGN010_HEPG2_24H:G12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 10.0 |
| CHMP6 | charged multivesicular body protein 6 | 7.30382 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 6.3526 |
| LOC122526780 | uncharacterized LOC122526780 | 6.16105 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 5.17041 |
| UBQLN2 | ubiquilin 2 | 5.01789 |
| SQOR | sulfide quinone oxidoreductase | 4.91606 |
| DENND2D | DENN/MADD domain containing 2D | 4.85225 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 4.75035 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.64419 |
| STK10 | serine/threonine kinase 10 | 4.47703 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.37357 |
| BZW2 | basic leucine zipper and W2 domains 2 | 4.35858 |
| TEX10 | testis expressed 10 | 4.17426 |
| SFTPB | surfactant protein B | 3.48802 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 3.3692 |
| NOSIP | nitric oxide synthase interacting protein | 3.34511 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 3.20776 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.9595 |
| RRAGA | Ras-related GTP binding A | 2.75196 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 2.34465 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 2.31505 |
| HBA1 | hemoglobin, alpha 1 | 2.29675 |
| ZFYVE21 | zinc finger, FYVE domain containing 21 | 2.29362 |
| ADAM10 | ADAM metallopeptidase domain 10 | 2.28082 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.24045 |
| TMEM51 | transmembrane protein 51 | 2.23723 |
| E2F2 | E2F transcription factor 2 | 2.18538 |
| KRT13 | keratin 13, type I | 2.17699 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 2.11234 |
| TLK2 | tousled-like kinase 2 | 2.05782 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 2.01805 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -6.38862 |
| CCDC86 | coiled-coil domain containing 86 | -5.47268 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -5.00909 |
| PCNA | proliferating cell nuclear antigen | -4.7987 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -4.56729 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.3013 |
| CCNB1 | cyclin B1 | -4.24259 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.22434 |
| ZNF586 | zinc finger protein 586 | -3.64957 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.59697 |
| ADI1 | acireductone dioxygenase 1 | -3.5369 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.32929 |
| CCNB2 | cyclin B2 | -2.91925 |
| TLCD3A | TLC domain containing 3A | -2.90449 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.73661 |
| LAP3 | leucine aminopeptidase 3 | -2.73559 |
| VDAC1 | voltage-dependent anion channel 1 | -2.55063 |
| LGMN | legumain | -2.50944 |
| TXNDC9 | thioredoxin domain containing 9 | -2.389 |
| MRPS16 | mitochondrial ribosomal protein S16 | -2.36473 |
| WASHC4 | WASH complex subunit 4 | -2.31443 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.25207 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.2436 |
| SLC35F2 | solute carrier family 35, member F2 | -2.18359 |
| MUC13 | mucin 13, cell surface associated | -2.0955 |
| TM4SF20 | transmembrane 4 L six family member 20 | -2.07285 |
| TMC5 | transmembrane channel-like 5 | -2.01166 |
