CRCGN010_HEPG2_24H:G18 Gene Set
Genes
37 genes differentially expressed following the CRCGN010_HEPG2_24H:G18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.607
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.5056
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.42635
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.34906
|
|
TXNL4B
|
thioredoxin-like 4B
|
3.67356
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.10709
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.76293
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.72569
|
|
PKN1
|
protein kinase N1
|
2.71929
|
|
CHN1
|
chimerin 1
|
2.47893
|
|
MAP7
|
microtubule-associated protein 7
|
2.41481
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.36241
|
|
PSMA3
|
proteasome (prosome, macropain) subunit, alpha type, 3
|
2.2446
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.2013
|
|
CDC45
|
cell division cycle 45
|
2.1767
|
|
KLHL9
|
kelch-like family member 9
|
2.13988
|
|
SUMF2
|
sulfatase modifying factor 2
|
2.13693
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-8.7203
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.05194
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.99108
|
|
DUSP6
|
dual specificity phosphatase 6
|
-4.92385
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.51378
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-4.29941
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.39451
|
|
CCNB1
|
cyclin B1
|
-3.37589
|
|
RALB
|
v-ral simian leukemia viral oncogene homolog B
|
-3.28257
|
|
TLR4
|
toll-like receptor 4
|
-2.89942
|
|
GNAS
|
GNAS complex locus
|
-2.85275
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.70438
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.54343
|
|
TRAPPC6A
|
trafficking protein particle complex 6A
|
-2.49149
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.35615
|
|
IGSF1
|
immunoglobulin superfamily, member 1
|
-2.13027
|
|
ZNF385D
|
zinc finger protein 385D
|
-2.11575
|
|
HMG20B
|
high mobility group 20B
|
-2.02507
|
|
UNC5C
|
unc-5 homolog C (C. elegans)
|
-2.01735
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.01574
|
