CRCGN010_HEPG2_24H:G19 Gene Set
Genes
44 genes differentially expressed following the CRCGN010_HEPG2_24H:G19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STIMATE
|
STIM activating enhancer
|
7.55327
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.58574
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.03882
|
|
LOC122526780
|
uncharacterized LOC122526780
|
4.01677
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.9774
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
3.94304
|
|
NOTCH1
|
notch 1
|
3.91708
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
3.84176
|
|
CYCS
|
cytochrome c, somatic
|
3.76662
|
|
E2F2
|
E2F transcription factor 2
|
3.49641
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.2786
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.95502
|
|
ECH1
|
enoyl CoA hydratase 1, peroxisomal
|
2.9317
|
|
MAP7
|
microtubule-associated protein 7
|
2.79351
|
|
HDGFL3
|
HDGF like 3
|
2.68058
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.55497
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.45761
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.36682
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.33644
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.24248
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.15186
|
|
KLHL9
|
kelch-like family member 9
|
2.05786
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.01853
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-7.42953
|
|
PCNA
|
proliferating cell nuclear antigen
|
-6.31824
|
|
YME1L1
|
YME1-like 1 ATPase
|
-4.77742
|
|
TUBB6
|
tubulin, beta 6 class V
|
-4.65894
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.36445
|
|
CCNB1
|
cyclin B1
|
-4.07575
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-3.98844
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.87596
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.74976
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.62373
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.71174
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.53628
|
|
CCNB2
|
cyclin B2
|
-2.43646
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.3467
|
|
PSRC1
|
proline/serine-rich coiled-coil 1
|
-2.30453
|
|
PRSS21
|
protease, serine, 21 (testisin)
|
-2.26954
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.26167
|
|
SYNGAP1
|
synaptic Ras GTPase activating protein 1
|
-2.23574
|
|
LDHD
|
lactate dehydrogenase D
|
-2.23367
|
|
RBM34
|
RNA binding motif protein 34
|
-2.07155
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.00859
|