CRCGN010_HEPG2_24H:G21 Gene Set
Genes
49 genes differentially expressed following the CRCGN010_HEPG2_24H:G21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
6.87136
|
|
CHN1
|
chimerin 1
|
6.22952
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.63377
|
|
CSK
|
c-src tyrosine kinase
|
4.58167
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
4.56777
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.43077
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.91726
|
|
MAP7
|
microtubule-associated protein 7
|
3.78209
|
|
SATB1
|
SATB homeobox 1
|
3.63026
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.52769
|
|
VGLL4
|
vestigial-like family member 4
|
3.06834
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.85624
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.82525
|
|
CCNF
|
cyclin F
|
2.78895
|
|
SQOR
|
sulfide quinone oxidoreductase
|
2.48489
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.24722
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.23132
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.15968
|
|
SNX7
|
sorting nexin 7
|
2.08427
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.03755
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-6.6863
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-5.74823
|
|
CCNB2
|
cyclin B2
|
-4.84338
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
-4.45702
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-4.13682
|
|
WASHC4
|
WASH complex subunit 4
|
-4.11384
|
|
ZW10
|
zw10 kinetochore protein
|
-4.00529
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.88906
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.7873
|
|
NUP85
|
nucleoporin 85kDa
|
-3.5719
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.41204
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.106
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.67789
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.65013
|
|
LDHD
|
lactate dehydrogenase D
|
-2.60268
|
|
SNX11
|
sorting nexin 11
|
-2.58602
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.41727
|
|
LLGL2
|
lethal giant larvae homolog 2 (Drosophila)
|
-2.38887
|
|
ZNF586
|
zinc finger protein 586
|
-2.35203
|
|
RNF167
|
ring finger protein 167
|
-2.28767
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.24309
|
|
PALM
|
paralemmin
|
-2.20738
|
|
PROS1
|
protein S (alpha)
|
-2.20512
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.18913
|
|
BDKRB2
|
bradykinin receptor B2
|
-2.17747
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.14629
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.13823
|
|
TRAPPC6A
|
trafficking protein particle complex 6A
|
-2.05507
|
|
TMEM131
|
transmembrane protein 131
|
-2.00538
|
