CRCGN010_HEPG2_24H:G22 Gene Set
Genes
54 genes differentially expressed following the CRCGN010_HEPG2_24H:G22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
7.7034
|
|
CBR3
|
carbonyl reductase 3
|
5.15589
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.74314
|
|
MYLK
|
myosin light chain kinase
|
4.32728
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.55312
|
|
PRKCH
|
protein kinase C, eta
|
3.25902
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.15745
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.58639
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.54578
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.54053
|
|
SHC1
|
SHC (Src homology 2 domain containing) transforming protein 1
|
2.30811
|
|
PDLIM1
|
PDZ and LIM domain 1
|
2.2899
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.27825
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.2255
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.20415
|
|
MAP7
|
microtubule-associated protein 7
|
2.16627
|
|
EGF
|
epidermal growth factor
|
2.14829
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.09178
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.08008
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.05154
|
|
CSK
|
c-src tyrosine kinase
|
2.02651
|
|
HPS4
|
Hermansky-Pudlak syndrome 4
|
2.00882
|
|
ARAP2
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
|
2.0066
|
|
DPM3
|
dolichyl-phosphate mannosyltransferase polypeptide 3
|
2.00517
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.29998
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-5.22683
|
|
VAT1
|
vesicle amine transport 1
|
-4.8183
|
|
CCNB2
|
cyclin B2
|
-4.68506
|
|
TCTN1
|
tectonic family member 1
|
-4.43132
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.93291
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
-3.34858
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.27699
|
|
MTA1
|
metastasis associated 1
|
-3.20573
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.16747
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.09811
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.08189
|
|
TOR1A
|
torsin family 1, member A (torsin A)
|
-2.98525
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-2.9638
|
|
HMG20B
|
high mobility group 20B
|
-2.94045
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-2.85263
|
|
WASHC4
|
WASH complex subunit 4
|
-2.80905
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.7998
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-2.6633
|
|
CCNB1
|
cyclin B1
|
-2.63225
|
|
TLR4
|
toll-like receptor 4
|
-2.40984
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.32957
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.25617
|
|
TBKBP1
|
TBK1 binding protein 1
|
-2.20644
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.19227
|
|
RNF167
|
ring finger protein 167
|
-2.1356
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.08465
|
|
SAR1B
|
secretion associated, Ras related GTPase 1B
|
-2.07936
|
|
SIRT2
|
sirtuin 2
|
-2.02749
|
|
HAAO
|
3-hydroxyanthranilate 3,4-dioxygenase
|
-2.0038
|
