CRCGN010_HEPG2_24H:G23 Gene Set
Genes
54 genes differentially expressed following the CRCGN010_HEPG2_24H:G23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.72247
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
4.27388
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.31752
|
|
CSK
|
c-src tyrosine kinase
|
3.31618
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.16383
|
|
EPHB2
|
EPH receptor B2
|
3.08723
|
|
CTSL
|
cathepsin L
|
2.87885
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.84615
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.84413
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.80222
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
2.55907
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.5293
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.4688
|
|
MAP7
|
microtubule-associated protein 7
|
2.42229
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.38101
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.35741
|
|
BAMBI
|
BMP and activin membrane-bound inhibitor
|
2.2784
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.26456
|
|
VGLL4
|
vestigial-like family member 4
|
2.25216
|
|
ADGRG1
|
adhesion G protein-coupled receptor G1
|
2.22811
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.17055
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.15917
|
|
FZD7
|
frizzled class receptor 7
|
2.12115
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.11141
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.10513
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-5.67166
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-4.57343
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-4.33996
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.75748
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.67662
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.45408
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.39403
|
|
DNM1L
|
dynamin 1-like
|
-3.37195
|
|
CCNB2
|
cyclin B2
|
-3.31398
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.30079
|
|
SESN1
|
sestrin 1
|
-3.21775
|
|
LDHD
|
lactate dehydrogenase D
|
-3.0171
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-3.0013
|
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-2.99423
|
|
NISCH
|
nischarin
|
-2.94303
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.90011
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.80571
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.6423
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.63177
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.56375
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.49444
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.37039
|
|
ZW10
|
zw10 kinetochore protein
|
-2.33189
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.30834
|
|
TLR4
|
toll-like receptor 4
|
-2.23149
|
|
NEFM
|
neurofilament, medium polypeptide
|
-2.17492
|
|
DDAH1
|
dimethylarginine dimethylaminohydrolase 1
|
-2.1115
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.02626
|
|
STMN1
|
stathmin 1
|
-2.01942
|
