CRCGN010_HEPG2_24H:G24 Gene Set
Genes
46 genes differentially expressed following the CRCGN010_HEPG2_24H:G24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
5.23081
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
4.21839
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.71837
|
|
TXNL4B
|
thioredoxin-like 4B
|
3.55481
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.51272
|
|
MEST
|
mesoderm specific transcript
|
3.41283
|
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
3.39535
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.13222
|
|
NOTCH1
|
notch 1
|
3.11841
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
3.0933
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.06231
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.03442
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.92842
|
|
STK10
|
serine/threonine kinase 10
|
2.88407
|
|
FPGS
|
folylpolyglutamate synthase
|
2.87317
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.84237
|
|
EPN2
|
epsin 2
|
2.7654
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
2.60087
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.46238
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.38459
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.36974
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.26209
|
|
STIMATE
|
STIM activating enhancer
|
2.1818
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.17315
|
|
MSTO1
|
misato 1, mitochondrial distribution and morphology regulator
|
2.03698
|
|
CSK
|
c-src tyrosine kinase
|
2.01849
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-10.0
|
|
CD320
|
CD320 molecule
|
-5.61089
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.48283
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.44095
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-4.35401
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.09666
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.06281
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.85466
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.78385
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.72949
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.45544
|
|
RPN1
|
ribophorin I
|
-3.12519
|
|
TLR4
|
toll-like receptor 4
|
-2.76052
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.73839
|
|
RPIA
|
ribose 5-phosphate isomerase A
|
-2.71885
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.66729
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-2.44236
|
|
RAI14
|
retinoic acid induced 14
|
-2.40112
|
|
WASHC4
|
WASH complex subunit 4
|
-2.28714
|
|
PRR3
|
proline rich 3
|
-2.23476
|
