| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | methenamine 39.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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47 genes differentially expressed following the CRCGN010_HEPG2_24H:H01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.99439 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 4.45086 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 4.10735 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 4.00312 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.92972 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 3.89171 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.84366 |
| UBQLN2 | ubiquilin 2 | 3.61785 |
| CHMP6 | charged multivesicular body protein 6 | 3.61312 |
| RPL39L | ribosomal protein L39-like | 3.59687 |
| LCN2 | lipocalin 2 | 3.53564 |
| HOXA10 | homeobox A10 | 3.53204 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.52378 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.4053 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.28359 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 3.27448 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.94788 |
| STXBP1 | syntaxin binding protein 1 | 2.93369 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 2.85146 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 2.69997 |
| MAP7 | microtubule-associated protein 7 | 2.54979 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.38713 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.35356 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.28679 |
| PFKL | phosphofructokinase, liver | 2.20588 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.1639 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | -5.96588 |
| TLR4 | toll-like receptor 4 | -3.83223 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.81983 |
| DDIT4 | DNA-damage-inducible transcript 4 | -3.71513 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | -3.66935 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.34768 |
| CHMP4B | charged multivesicular body protein 4B | -3.12089 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.04959 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.94661 |
| SMNDC1 | survival motor neuron domain containing 1 | -2.81876 |
| VDAC1 | voltage-dependent anion channel 1 | -2.80187 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -2.56589 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.49767 |
| SLC35F2 | solute carrier family 35, member F2 | -2.37934 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.33159 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.29689 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.24344 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -2.15313 |
| GNAS | GNAS complex locus | -2.08776 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.0472 |
| ZNF322 | zinc finger protein 322 | -2.0367 |
