CRCGN010_HEPG2_24H:H02 Gene Set
Genes
50 genes differentially expressed following the CRCGN010_HEPG2_24H:H02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CYCS
|
cytochrome c, somatic
|
4.7163
|
|
LCN2
|
lipocalin 2
|
3.86033
|
|
NMU
|
neuromedin U
|
3.6731
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.47707
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.4113
|
|
MYLK
|
myosin light chain kinase
|
3.3773
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
3.34763
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.31607
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.23123
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.2067
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
3.17613
|
|
STK10
|
serine/threonine kinase 10
|
3.16615
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.9282
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.87603
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.8698
|
|
UBQLN2
|
ubiquilin 2
|
2.84497
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.82529
|
|
RRAGA
|
Ras-related GTP binding A
|
2.78857
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.72422
|
|
MAP7
|
microtubule-associated protein 7
|
2.68672
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.58917
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.543
|
|
MOK
|
MOK protein kinase
|
2.4912
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.47387
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.31484
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.23583
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.20673
|
|
SCRN1
|
secernin 1
|
2.19003
|
|
CHN1
|
chimerin 1
|
2.0433
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.0314
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.5549
|
|
ZNF586
|
zinc finger protein 586
|
-5.58877
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-4.37413
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.27913
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.7505
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-3.64863
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.51543
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.38133
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.2875
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.20117
|
|
LDHD
|
lactate dehydrogenase D
|
-3.1176
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.02673
|
|
CD320
|
CD320 molecule
|
-2.89313
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.82
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.58837
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.5343
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.38847
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.30797
|
|
C5
|
complement component 5
|
-2.16943
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-2.12087
|
