| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | methenamine 4.97 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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62 genes differentially expressed following the CRCGN010_HEPG2_24H:H04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHMP6 | charged multivesicular body protein 6 | 4.59737 |
| LCN2 | lipocalin 2 | 4.57234 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.55925 |
| ATP11B | ATPase, class VI, type 11B | 4.43974 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.36175 |
| CDC45 | cell division cycle 45 | 4.34658 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.27715 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.25018 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.17961 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.11264 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.0266 |
| EPHA3 | EPH receptor A3 | 3.78585 |
| PRR15L | proline rich 15-like | 3.76091 |
| ADAM10 | ADAM metallopeptidase domain 10 | 3.65084 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.41019 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.38461 |
| GPATCH8 | G patch domain containing 8 | 2.86508 |
| CHEK2 | checkpoint kinase 2 | 2.78493 |
| MAP7 | microtubule-associated protein 7 | 2.6861 |
| H2BC12 | H2B clustered histone 12 | 2.65407 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.52143 |
| CTTN | cortactin | 2.4435 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.39898 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | 2.28584 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.27111 |
| ZNF318 | zinc finger protein 318 | 2.24753 |
| MMP10 | matrix metallopeptidase 10 | 2.17988 |
| LOC122526780 | uncharacterized LOC122526780 | 2.08401 |
| SFTPB | surfactant protein B | 2.06453 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.0154 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -7.69322 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -7.62217 |
| DNM1L | dynamin 1-like | -5.27956 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.20539 |
| ISOC1 | isochorismatase domain containing 1 | -4.8214 |
| ZNF586 | zinc finger protein 586 | -4.56549 |
| LDHD | lactate dehydrogenase D | -4.51771 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -4.49233 |
| TSPAN4 | tetraspanin 4 | -4.45142 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -4.33965 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.30801 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.21686 |
| CHMP4B | charged multivesicular body protein 4B | -3.89361 |
| TLR4 | toll-like receptor 4 | -3.27892 |
| GNAS | GNAS complex locus | -3.13734 |
| SNX11 | sorting nexin 11 | -3.09741 |
| TLCD3A | TLC domain containing 3A | -2.96054 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.86578 |
| ERGIC2 | ERGIC and golgi 2 | -2.66604 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial | -2.3836 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | -2.31373 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -2.22318 |
| ZNF500 | zinc finger protein 500 | -2.19725 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.1655 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -2.14641 |
| TMEM147 | transmembrane protein 147 | -2.14044 |
| HMOX2 | heme oxygenase 2 | -2.13619 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 | -2.12817 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -2.12299 |
| PDHX | pyruvate dehydrogenase complex, component X | -2.05991 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.04154 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 | -2.03319 |
