| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | methenamine 2.49 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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60 genes differentially expressed following the CRCGN010_HEPG2_24H:H05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 8.66506 |
| ATP11B | ATPase, class VI, type 11B | 8.31011 |
| GSTZ1 | glutathione S-transferase zeta 1 | 8.04843 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 7.97648 |
| PLSCR1 | phospholipid scramblase 1 | 6.68318 |
| CCL2 | chemokine (C-C motif) ligand 2 | 5.5868 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.21394 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.03769 |
| INTS3 | integrator complex subunit 3 | 4.84158 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.48021 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.38715 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 4.36387 |
| MAP7 | microtubule-associated protein 7 | 4.21853 |
| CBR3 | carbonyl reductase 3 | 3.98581 |
| DIPK1A | divergent protein kinase domain 1A | 3.95753 |
| LCN2 | lipocalin 2 | 3.87105 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.63821 |
| CYCS | cytochrome c, somatic | 3.55007 |
| SATB1 | SATB homeobox 1 | 3.52623 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 3.24646 |
| EPHA3 | EPH receptor A3 | 3.0794 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.97819 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.94635 |
| STIMATE | STIM activating enhancer | 2.91442 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.62474 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 2.417 |
| EVL | Enah/Vasp-like | 2.41246 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.39208 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 | 2.38685 |
| NUP133 | nucleoporin 133kDa | 2.37463 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.04849 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GOLT1B | golgi transport 1B | -5.35491 |
| LAP3 | leucine aminopeptidase 3 | -4.83118 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.56456 |
| SLC35F2 | solute carrier family 35, member F2 | -4.48794 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.3895 |
| SCAND1 | SCAN domain containing 1 | -4.14604 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -4.01371 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.00797 |
| CCNB2 | cyclin B2 | -3.79749 |
| VAT1 | vesicle amine transport 1 | -3.79728 |
| COG2 | component of oligomeric golgi complex 2 | -3.73723 |
| ZNF586 | zinc finger protein 586 | -3.6653 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.60844 |
| SPAG4 | sperm associated antigen 4 | -3.51261 |
| NVL | nuclear VCP-like | -3.47569 |
| SNX11 | sorting nexin 11 | -3.43699 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -3.36127 |
| DCK | deoxycytidine kinase | -3.25462 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.15368 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.9949 |
| SESN1 | sestrin 1 | -2.93112 |
| GNAS | GNAS complex locus | -2.6101 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.47871 |
| ETNK2 | ethanolamine kinase 2 | -2.42797 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.26808 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.24356 |
| PDZD2 | PDZ domain containing 2 | -2.18396 |
| TBC1D13 | TBC1 domain family, member 13 | -2.16562 |
| MED27 | mediator complex subunit 27 | -2.08983 |
