| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | methenamine 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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50 genes differentially expressed following the CRCGN010_HEPG2_24H:H06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CCL2 | chemokine (C-C motif) ligand 2 | 5.78315 |
| CYCS | cytochrome c, somatic | 4.58476 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.2102 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.05743 |
| MAMLD1 | mastermind-like domain containing 1 | 4.00985 |
| SOCS2 | suppressor of cytokine signaling 2 | 3.72881 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 3.5103 |
| PNKP | polynucleotide kinase 3'-phosphatase | 3.49205 |
| CSK | c-src tyrosine kinase | 3.4607 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.35198 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 3.06804 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.9686 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.82734 |
| NOTCH1 | notch 1 | 2.79964 |
| GATA3 | GATA binding protein 3 | 2.72582 |
| AXIN1 | axin 1 | 2.6956 |
| RAB21 | RAB21, member RAS oncogene family | 2.66476 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.66468 |
| ZFP36 | ZFP36 ring finger protein | 2.56564 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.54152 |
| PLSCR1 | phospholipid scramblase 1 | 2.54129 |
| DENND2D | DENN/MADD domain containing 2D | 2.50364 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 2.50032 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 2.33405 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.31852 |
| HMOX1 | heme oxygenase 1 | 2.1877 |
| NGRN | neugrin, neurite outgrowth associated | 2.18085 |
| MAP7 | microtubule-associated protein 7 | 2.12218 |
| MCM3 | minichromosome maintenance complex component 3 | 2.01094 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | -5.69211 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.76424 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.6191 |
| SLC35F2 | solute carrier family 35, member F2 | -3.99162 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.83707 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -3.48757 |
| RBM15B | RNA binding motif protein 15B | -3.47365 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.17624 |
| COG2 | component of oligomeric golgi complex 2 | -3.01046 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.99052 |
| TLR4 | toll-like receptor 4 | -2.89206 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -2.86469 |
| PRPF4 | pre-mRNA processing factor 4 | -2.74761 |
| LDHD | lactate dehydrogenase D | -2.69633 |
| VAT1 | vesicle amine transport 1 | -2.68422 |
| CCNB2 | cyclin B2 | -2.67215 |
| WASHC4 | WASH complex subunit 4 | -2.55156 |
| FHL2 | four and a half LIM domains 2 | -2.4666 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.33336 |
| GNAS | GNAS complex locus | -2.33142 |
| PPOX | protoporphyrinogen oxidase | -2.07005 |
