CRCGN010_HEPG2_24H:H08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description triclosan 20.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

518 genes differentially expressed following the CRCGN010_HEPG2_24H:H08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
INPP1 inositol polyphosphate-1-phosphatase 9.5698
KIFBP kinesin family binding protein 8.46177
TIMP2 TIMP metallopeptidase inhibitor 2 8.32899
HMOX1 heme oxygenase 1 7.0163
TXNRD1 thioredoxin reductase 1 7.01555
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 6.87167
TRIB3 tribbles pseudokinase 3 6.7627
MVP major vault protein 6.53269
SQSTM1 sequestosome 1 6.38976
NR1H2 nuclear receptor subfamily 1, group H, member 2 6.10776
CDPF1 cysteine-rich, DPF motif domain containing 1 6.02342
FHL2 four and a half LIM domains 2 5.8586
SQOR sulfide quinone oxidoreductase 5.69337
ZFP36 ZFP36 ring finger protein 5.52733
IGFBP3 insulin-like growth factor binding protein 3 5.50772
PNKP polynucleotide kinase 3'-phosphatase 5.47563
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 5.32439
STX1A syntaxin 1A (brain) 5.30789
FOSL1 FOS-like antigen 1 5.28798
EGR1 early growth response 1 5.15692
IER3 immediate early response 3 5.14892
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 5.12129
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.98355
ADGRE5 adhesion G protein-coupled receptor E5 4.95863
VAT1 vesicle amine transport 1 4.82256
ACOT9 acyl-CoA thioesterase 9 4.8167
GRB10 growth factor receptor-bound protein 10 4.58424
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 4.44899
LRP10 low density lipoprotein receptor-related protein 10 4.44263
LCN2 lipocalin 2 4.42643
GLRX glutaredoxin (thioltransferase) 4.34628
TRIB1 tribbles pseudokinase 1 4.33901
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 4.27573
AARS1 alanyl-tRNA synthetase 1 4.22565
NANOS3 nanos homolog 3 (Drosophila) 4.20144
GFPT1 glutamine--fructose-6-phosphate transaminase 1 4.16912
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 4.09607
DDIT4 DNA-damage-inducible transcript 4 4.03764
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 4.03489
GSTZ1 glutathione S-transferase zeta 1 4.00624
IL4R interleukin 4 receptor 3.97726
MBNL2 muscleblind-like splicing regulator 2 3.96602
DSG2 desmoglein 2 3.96537
BZW2 basic leucine zipper and W2 domains 2 3.95338
CASC3 cancer susceptibility candidate 3 3.90569
UBQLN2 ubiquilin 2 3.88825
GTPBP2 GTP binding protein 2 3.87413
YARS1 tyrosyl-tRNA synthetase 1 3.80057
RALB v-ral simian leukemia viral oncogene homolog B 3.65386
TOMM34 translocase of outer mitochondrial membrane 34 3.64663
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 3.6192
SHB Src homology 2 domain containing adaptor protein B 3.58766
PRAF2 PRA1 domain family, member 2 3.57657
PDGFA platelet-derived growth factor alpha polypeptide 3.57116
RAP1GAP RAP1 GTPase activating protein 3.5667
MYC v-myc avian myelocytomatosis viral oncogene homolog 3.56198
PTK2 protein tyrosine kinase 2 3.51435
ITGB5 integrin, beta 5 3.46222
FOXO4 forkhead box O4 3.39429
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 3.38252
LGALS8 lectin, galactoside-binding, soluble, 8 3.352
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 3.34258
WDR13 WD repeat domain 13 3.29653
SMAD3 SMAD family member 3 3.25639
PRKCD protein kinase C, delta 3.24201
PPARD peroxisome proliferator-activated receptor delta 3.23477
OSGIN2 oxidative stress induced growth inhibitor family member 2 3.23117
SARS1 seryl-tRNA synthetase 1 3.2162
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 3.17215
STK10 serine/threonine kinase 10 3.14293
VSIG2 V-set and immunoglobulin domain containing 2 3.12683
NPC1 Niemann-Pick disease, type C1 3.11503
RAB11FIP2 RAB11 family interacting protein 2 (class I) 3.10894
PTPN12 protein tyrosine phosphatase, non-receptor type 12 3.06922
FYN FYN proto-oncogene, Src family tyrosine kinase 3.06217
NUP58 nucleoporin 58 3.02606
SFXN3 sideroflexin 3 2.99444
TARS1 threonyl-tRNA synthetase 1 2.98753
GARS1 glycyl-tRNA synthetase 1 2.9844
DUSP6 dual specificity phosphatase 6 2.95523
PPARG peroxisome proliferator-activated receptor gamma 2.94842
MGLL monoglyceride lipase 2.92175
TERF2IP telomeric repeat binding factor 2, interacting protein 2.92053
NPDC1 neural proliferation, differentiation and control, 1 2.91796
MCOLN1 mucolipin 1 2.90473
PXDC1 PX domain containing 1 2.88875
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.88244
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.87796
TRIM13 tripartite motif containing 13 2.87568
YIPF3 Yip1 domain family, member 3 2.86522
UGDH UDP-glucose 6-dehydrogenase 2.85925
CLDN4 claudin 4 2.85254
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.83916
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.82455
LOC102724560 cystathionine beta-synthase 2.80704
SH2B3 SH2B adaptor protein 3 2.78285
LOC128125814 uncharacterized LOC128125814 2.77384
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 2.76989
CXCL2 chemokine (C-X-C motif) ligand 2 2.7696
KLHL21 kelch-like family member 21 2.7668
EPN2 epsin 2 2.7654
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.75874
CEP57 centrosomal protein 57kDa 2.75323
SNX6 sorting nexin 6 2.74852
CDK7 cyclin-dependent kinase 7 2.73939
RBKS ribokinase 2.7385
CEMIP2 cell migration inducing hyaluronidase 2 2.73167
STAP2 signal transducing adaptor family member 2 2.70794
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 2.68347
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.66327
SKIC2 SKI2 subunit of superkiller complex 2.65629
NMU neuromedin U 2.64706
PELO pelota homolog (Drosophila) 2.61615
BCL2L13 BCL2-like 13 (apoptosis facilitator) 2.61475
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.60188
CARS1 cysteinyl-tRNA synthetase 1 2.59992
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.58096
WARS1 tryptophanyl-tRNA synthetase 1 2.57394
ZFP69B ZFP69 zinc finger protein B 2.55999
CDC37L1 cell division cycle 37-like 1 2.55966
ABHD6 abhydrolase domain containing 6 2.549
CHIC2 cysteine-rich hydrophobic domain 2 2.54618
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.54112
SERINC1 serine incorporator 1 2.53963
ATP9A ATPase, class II, type 9A 2.53894
ZBTB10 zinc finger and BTB domain containing 10 2.53879
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 2.53788
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 2.53665
IL37 interleukin 37 2.53469
TLN1 talin 1 2.52379
KIAA0513 KIAA0513 2.51215
DYNLT1 dynein, light chain, Tctex-type 1 2.51067
ATF6 activating transcription factor 6 2.49648
CLTB clathrin, light chain B 2.47984
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.47857
CDA cytidine deaminase 2.47619
CSNK1E casein kinase 1, epsilon 2.4665
PRSS8 protease, serine, 8 2.46323
TEAD3 TEA domain family member 3 2.46077
ATF3 activating transcription factor 3 2.45304
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 2.44924
EVL Enah/Vasp-like 2.43747
GPC1 glypican 1 2.42575
BLVRA biliverdin reductase A 2.41836
IGF2R insulin-like growth factor 2 receptor 2.41722
NUPR1 nuclear protein, transcriptional regulator, 1 2.41594
HPS5 Hermansky-Pudlak syndrome 5 2.41204
FLOT1 flotillin 1 2.41059
CNPY3 canopy FGF signaling regulator 3 2.41058
PRKCQ protein kinase C, theta 2.40682
DMAC2L distal membrane arm assembly component 2 like 2.40494
GABARAPL1 GABA(A) receptor-associated protein like 1 2.384
RGL2 ral guanine nucleotide dissociation stimulator-like 2 2.37298
FBXO7 F-box protein 7 2.36535
SOX4 SRY (sex determining region Y)-box 4 2.36534
PLAAT1 phospholipase A and acyltransferase 1 2.36484
DNM1 dynamin 1 2.35396
PFDN1 prefoldin subunit 1 2.34934
UFM1 ubiquitin-fold modifier 1 2.34629
ZMIZ1 zinc finger, MIZ-type containing 1 2.34393
SNX7 sorting nexin 7 2.33112
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 2.3302
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.32291
ASCC1 activating signal cointegrator 1 complex subunit 1 2.31579
AMOTL2 angiomotin like 2 2.31295
NAPSA napsin A aspartic peptidase 2.30941
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.30605
S100A13 S100 calcium binding protein A13 2.3057
INTS6 integrator complex subunit 6 2.30555
CYCS cytochrome c, somatic 2.30331
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.3025
TBC1D15 TBC1 domain family, member 15 2.29306
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 2.28285
DYNLT3 dynein, light chain, Tctex-type 3 2.28158
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.27829
RAI14 retinoic acid induced 14 2.27766
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 2.27458
GDI1 GDP dissociation inhibitor 1 2.26811
ASL argininosuccinate lyase 2.26317
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 2.26112
IGFBP1 insulin-like growth factor binding protein 1 2.25799
TSPAN4 tetraspanin 4 2.25782
DUSP3 dual specificity phosphatase 3 2.25705
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 2.25253
PHOSPHO2-KLHL23 PHOSPHO2-KLHL23 readthrough 2.25231
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.24923
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 2.2451
BAG6 BCL2-associated athanogene 6 2.24442
TRIM8 tripartite motif containing 8 2.22996
BCHE butyrylcholinesterase 2.2297
PFKP phosphofructokinase, platelet 2.21751
RAP1A RAP1A, member of RAS oncogene family 2.21639
ADGRG1 adhesion G protein-coupled receptor G1 2.21502
ZBTB20 zinc finger and BTB domain containing 20 2.21394
MBNL1 muscleblind-like splicing regulator 1 2.20702
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 2.20432
CAMTA2 calmodulin binding transcription activator 2 2.20078
RXYLT1 ribitol xylosyltransferase 1 2.19871
JOSD1 Josephin domain containing 1 2.19414
DUSP8 dual specificity phosphatase 8 2.18504
SH3GLB1 SH3-domain GRB2-like endophilin B1 2.17976
BYSL bystin-like 2.17082
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.16959
UBXN7 UBX domain protein 7 2.16652
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2.16403
WBP4 WW domain binding protein 4 2.16104
ST18 suppression of tumorigenicity 18, zinc finger 2.1436
CAMTA1 calmodulin binding transcription activator 1 2.14007
UBA1 ubiquitin-like modifier activating enzyme 1 2.13513
ISG15 ISG15 ubiquitin-like modifier 2.12798
PYGB phosphorylase, glycogen; brain 2.12328
MAP1S microtubule-associated protein 1S 2.11423
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.10972
CLTA clathrin, light chain A 2.10103
RBPJ recombination signal binding protein for immunoglobulin kappa J region 2.09718
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2.0959
FAM50A family with sequence similarity 50, member A 2.09433
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 2.09235
NT5E 5'-nucleotidase, ecto (CD73) 2.09202
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.08281
TRIM23 tripartite motif containing 23 2.07198
CDR2L cerebellar degeneration-related protein 2-like 2.07157
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.06176
C2CD2L C2CD2-like 2.05972
SHROOM2 shroom family member 2 2.05746
QTMAN queuosine-tRNA mannosyltransferase 2.05628
FASTKD5 FAST kinase domains 5 2.05278
MICALL1 MICAL-like 1 2.05276
GTF2IRD1 GTF2I repeat domain containing 1 2.05083
STXBP2 syntaxin binding protein 2 2.04911
C2CD2 C2 calcium-dependent domain containing 2 2.0403
BBIP1 BBSome interacting protein 1 2.0367
GNG12 guanine nucleotide binding protein (G protein), gamma 12 2.02925
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 2.02105
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 2.01855
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 2.01849
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.01485
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.01482
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.00966
ABLIM3 actin binding LIM protein family, member 3 2.00961
MYO1D myosin ID 2.0087

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -10.0
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -9.29256
TCTN1 tectonic family member 1 -8.96636
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -8.13728
B4GAT1 beta-1,4-glucuronyltransferase 1 -7.77425
AURKB aurora kinase B -7.48835
CDC20 cell division cycle 20 -7.41244
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -7.21907
STMN1 stathmin 1 -7.10712
PSRC1 proline/serine-rich coiled-coil 1 -6.65252
LDHD lactate dehydrogenase D -6.5907
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -6.49349
CCNA2 cyclin A2 -6.30457
ISOC1 isochorismatase domain containing 1 -6.20143
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -6.11259
CDK1 cyclin-dependent kinase 1 -5.88433
SOAT2 sterol O-acyltransferase 2 -5.75589
NT5DC2 5'-nucleotidase domain containing 2 -5.73615
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -5.60732
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -5.55614
TOP2A topoisomerase (DNA) II alpha 170kDa -5.55385
CCNB1 cyclin B1 -5.5399
TMEM97 transmembrane protein 97 -5.51545
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -5.41863
CD320 CD320 molecule -5.31718
CCNB2 cyclin B2 -5.31715
ZW10 zw10 kinetochore protein -5.25442
ADI1 acireductone dioxygenase 1 -5.23064
POLR1A polymerase (RNA) I polypeptide A, 194kDa -5.2104
PCNA proliferating cell nuclear antigen -4.95575
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -4.8199
PLK1 polo-like kinase 1 -4.73559
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -4.6446
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -4.61219
DERA deoxyribose-phosphate aldolase (putative) -4.56202
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -4.52184
PARP1 poly (ADP-ribose) polymerase 1 -4.48826
LBR lamin B receptor -4.44415
OXA1L oxidase (cytochrome c) assembly 1-like -4.3382
UBE2C ubiquitin-conjugating enzyme E2C -4.33209
HADH hydroxyacyl-CoA dehydrogenase -4.25173
FBXL12 F-box and leucine-rich repeat protein 12 -4.20662
BIRC5 baculoviral IAP repeat containing 5 -4.14768
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -4.08633
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -4.07684
RPIA ribose 5-phosphate isomerase A -3.98578
PGAM4 phosphoglycerate mutase family member 4 -3.96752
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -3.9535
GMNN geminin, DNA replication inhibitor -3.91092
ARF5 ADP-ribosylation factor 5 -3.83918
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -3.82064
TFDP1 transcription factor Dp-1 -3.81148
KIF14 kinesin family member 14 -3.76612
COG7 component of oligomeric golgi complex 7 -3.76225
TEDC2 tubulin epsilon and delta complex 2 -3.69653
MLEC malectin -3.68926
NUP85 nucleoporin 85kDa -3.66136
HAT1 histone acetyltransferase 1 -3.65093
ECH1 enoyl CoA hydratase 1, peroxisomal -3.6141
ASF1B anti-silencing function 1B histone chaperone -3.60904
DCK deoxycytidine kinase -3.54189
MELK maternal embryonic leucine zipper kinase -3.48873
KIFC1 kinesin family member C1 -3.46824
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -3.45492
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.42947
KIF15 kinesin family member 15 -3.40834
FAIM Fas apoptotic inhibitory molecule -3.40042
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.32882
TMEM109 transmembrane protein 109 -3.29302
INCENP inner centromere protein antigens 135/155kDa -3.2831
HSPB1 heat shock 27kDa protein 1 -3.27321
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -3.25642
CENPA centromere protein A -3.24398
EED embryonic ectoderm development -3.23018
TIMELESS timeless circadian clock -3.22794
TK1 thymidine kinase 1, soluble -3.22058
CDCA8 cell division cycle associated 8 -3.20857
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -3.20481
GLOD4 glyoxalase domain containing 4 -3.17038
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.16275
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -3.14818
MIS18A MIS18 kinetochore protein A -3.1358
CDCA3 cell division cycle associated 3 -3.12462
NRIP1 nuclear receptor interacting protein 1 -3.10714
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.09787
CDC45 cell division cycle 45 -3.08819
GAST gastrin -3.07574
NUP107 nucleoporin 107kDa -3.06606
CCNF cyclin F -3.05848
ACAA1 acetyl-CoA acyltransferase 1 -3.03297
RAD54L RAD54-like (S. cerevisiae) -3.02539
COQ3 coenzyme Q3 methyltransferase -3.01808
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -3.01288
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -3.0044
THAP11 THAP domain containing 11 -2.95977
TBC1D10C TBC1 domain family, member 10C -2.9531
CLDN15 claudin 15 -2.93598
CHEK2 checkpoint kinase 2 -2.93505
DSCC1 DNA replication and sister chromatid cohesion 1 -2.92962
LMNB1 lamin B1 -2.87484
ELAVL1 ELAV like RNA binding protein 1 -2.86558
PARN poly(A)-specific ribonuclease -2.85371
FOXM1 forkhead box M1 -2.84701
AVPR1B arginine vasopressin receptor 1B -2.83244
ALDOC aldolase C, fructose-bisphosphate -2.82272
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.82014
FEN1 flap structure-specific endonuclease 1 -2.81408
NCAPG2 non-SMC condensin II complex, subunit G2 -2.80822
PPP4C protein phosphatase 4, catalytic subunit -2.79552
RNASE7 ribonuclease, RNase A family, 7 -2.78111
MRPL16 mitochondrial ribosomal protein L16 -2.77333
NUP62 nucleoporin 62kDa -2.7729
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.76478
HMGA2 high mobility group AT-hook 2 -2.76128
MSH6 mutS homolog 6 -2.75931
FASTK Fas-activated serine/threonine kinase -2.75769
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.7501
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.74179
RPA3 replication protein A3, 14kDa -2.73287
CCNP cyclin P -2.71404
EPHA1 EPH receptor A1 -2.69991
GTF2A2 general transcription factor IIA, 2, 12kDa -2.69842
WEE1 WEE1 G2 checkpoint kinase -2.69084
HSPA1A heat shock 70kDa protein 1A -2.68331
ZWINT ZW10 interacting kinetochore protein -2.6776
PALB2 partner and localizer of BRCA2 -2.67175
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 -2.66553
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.65621
PXMP2 peroxisomal membrane protein 2, 22kDa -2.64744
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.64689
H2AX H2A.X variant histone -2.64342
CLASRP CLK4-associating serine/arginine rich protein -2.63156
CHL1 cell adhesion molecule L1-like -2.62705
TOR3A torsin family 3, member A -2.60127
CTSL cathepsin L -2.59709
CDKN3 cyclin-dependent kinase inhibitor 3 -2.59621
GLRX5 glutaredoxin 5 -2.58406
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.5802
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.57924
KIF11 kinesin family member 11 -2.57782
C5 complement component 5 -2.57674
TLR4 toll-like receptor 4 -2.56875
MRPL12 mitochondrial ribosomal protein L12 -2.56714
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma -2.55584
TROAP trophinin associated protein -2.5542
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 -2.55024
TSEN2 TSEN2 tRNA splicing endonuclease subunit -2.54683
VAV3 vav 3 guanine nucleotide exchange factor -2.54558
CASP3 caspase 3, apoptosis-related cysteine peptidase -2.54472
KIF18B kinesin family member 18B -2.54425
TSNAXIP1 translin-associated factor X interacting protein 1 -2.53307
LAGE3 L antigen family, member 3 -2.5263
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.52538
ERCC6L excision repair cross-complementation group 6-like -2.51881
POLK polymerase (DNA directed) kappa -2.51451
RNF208 ring finger protein 208 -2.4991
NCAPH non-SMC condensin I complex, subunit H -2.49388
CDT1 chromatin licensing and DNA replication factor 1 -2.49119
CENPX centromere protein X -2.48975
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -2.48384
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.47355
KIF4A kinesin family member 4A -2.46343
NUP37 nucleoporin 37kDa -2.46037
PGRMC1 progesterone receptor membrane component 1 -2.45719
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.45675
FBXO31 F-box protein 31 -2.44999
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.44964
RMI1 RecQ mediated genome instability 1 -2.44566
TPSG1 tryptase gamma 1 -2.43821
OIP5 Opa interacting protein 5 -2.43425
UNG uracil-DNA glycosylase -2.42173
TMEM14A transmembrane protein 14A -2.41936
MCM10 minichromosome maintenance complex component 10 -2.413
SLC66A3 solute carrier family 66 member 3 -2.4051
CDK2 cyclin-dependent kinase 2 -2.40237
MYCBP MYC binding protein -2.39205
RECQL4 RecQ protein-like 4 -2.38812
BLCAP bladder cancer associated protein -2.38588
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -2.38197
ERI2 ERI1 exoribonuclease family member 2 -2.37511
FANCI Fanconi anemia, complementation group I -2.36476
C2CD5 C2 calcium-dependent domain containing 5 -2.35817
CENPM centromere protein M -2.34955
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.34812
RAD51AP1 RAD51 associated protein 1 -2.33918
NEK2 NIMA-related kinase 2 -2.33791
MXD3 MAX dimerization protein 3 -2.33175
SLC22A14 solute carrier family 22, member 14 -2.32858
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.30512
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -2.29517
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 -2.29359
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.28997
ZNRF4 zinc and ring finger 4 -2.27385
MDH2 malate dehydrogenase 2, NAD (mitochondrial) -2.26036
PYCR3 pyrroline-5-carboxylate reductase 3 -2.25554
XPO1 exportin 1 -2.25432
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.25267
SAP130 Sin3A-associated protein, 130kDa -2.25093
PGAP2 post-GPI attachment to proteins 2 -2.25021
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -2.24858
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.24779
COPS7A COP9 signalosome subunit 7A -2.24674
SCAND1 SCAN domain containing 1 -2.24564
FGFR4 fibroblast growth factor receptor 4 -2.24447
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.23521
SDF2L1 stromal cell-derived factor 2-like 1 -2.23456
GPC3 glypican 3 -2.23433
CDC6 cell division cycle 6 -2.23192
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -2.22055
FN3KRP fructosamine 3 kinase related protein -2.211
NASP nuclear autoantigenic sperm protein (histone-binding) -2.21017
MSMO1 methylsterol monooxygenase 1 -2.20758
PECR peroxisomal trans-2-enoyl-CoA reductase -2.20632
WRAP53 WD repeat containing, antisense to TP53 -2.1968
NEO1 neogenin 1 -2.19401
CKAP5 cytoskeleton associated protein 5 -2.19372
CRELD2 cysteine-rich with EGF-like domains 2 -2.19196
CDK4 cyclin-dependent kinase 4 -2.19065
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.18949
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.18468
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -2.17895
UNC119B unc-119 homolog B (C. elegans) -2.17733
TMPRSS6 transmembrane protease, serine 6 -2.17616
GID8 GID complex subunit 8 -2.17521
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.1656
DEXI Dexi homolog (mouse) -2.16519
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.16026
KHK ketohexokinase (fructokinase) -2.15924
QTRT1 queuine tRNA-ribosyltransferase 1 -2.15916
MKI67 marker of proliferation Ki-67 -2.1571
TATDN2 TatD DNase domain containing 2 -2.15609
RFC2 replication factor C (activator 1) 2, 40kDa -2.15562
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 -2.14785
CAV3 caveolin 3 -2.14209
RBBP7 retinoblastoma binding protein 7 -2.13907
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.13282
DHRS2 dehydrogenase/reductase (SDR family) member 2 -2.13243
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.1317
MRPS2 mitochondrial ribosomal protein S2 -2.12959
CARHSP1 calcium regulated heat stable protein 1, 24kDa -2.12769
RBM28 RNA binding motif protein 28 -2.12395
CDK14 cyclin-dependent kinase 14 -2.12344
EDA2R ectodysplasin A2 receptor -2.11888
CASP7 caspase 7, apoptosis-related cysteine peptidase -2.11698
ATP5F1A ATP synthase F1 subunit alpha -2.11697
CKS1B CDC28 protein kinase regulatory subunit 1B -2.11408
KLK12 kallikrein-related peptidase 12 -2.11169
PRDM12 PR domain containing 12 -2.11148
BCL7C B-cell CLL/lymphoma 7C -2.10966
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -2.10564
AURKA aurora kinase A -2.10447
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.10033
ELAC2 elaC ribonuclease Z 2 -2.09779
CCDC47 coiled-coil domain containing 47 -2.09149
C1QBP complement component 1, q subcomponent binding protein -2.08679
TRIP13 thyroid hormone receptor interactor 13 -2.08343
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -2.08076
FBXO5 F-box protein 5 -2.07581
TYR tyrosinase -2.07039
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.0696
COG4 component of oligomeric golgi complex 4 -2.06938
TCERG1 transcription elongation regulator 1 -2.06897
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) -2.06819
POLD3 polymerase (DNA-directed), delta 3, accessory subunit -2.0588
CENPE centromere protein E, 312kDa -2.05717
ABT1 activator of basal transcription 1 -2.04862
E2F1 E2F transcription factor 1 -2.03966
AUNIP aurora kinase A and ninein interacting protein -2.03205
RBM14-RBM4 RBM14-RBM4 readthrough -2.02473
SMC4 structural maintenance of chromosomes 4 -2.02225
GAMT guanidinoacetate N-methyltransferase -2.01888
CETN2 centrin, EF-hand protein, 2 -2.01782
MRPL39 mitochondrial ribosomal protein L39 -2.01758
RACGAP1 Rac GTPase activating protein 1 -2.01632
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.01557
CERS1 ceramide synthase 1 -2.01481
CHRND cholinergic receptor, nicotinic, delta (muscle) -2.00158