| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | triclosan 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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59 genes differentially expressed following the CRCGN010_HEPG2_24H:H10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABHD6 | abhydrolase domain containing 6 | 7.74995 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 5.39937 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.81252 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 4.63226 |
| CHN1 | chimerin 1 | 4.62653 |
| E2F2 | E2F transcription factor 2 | 4.47002 |
| GPATCH8 | G patch domain containing 8 | 4.0846 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.54946 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 3.48589 |
| MMP1 | matrix metallopeptidase 1 | 3.40982 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 3.33742 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.06451 |
| STK10 | serine/threonine kinase 10 | 2.92002 |
| MEST | mesoderm specific transcript | 2.89797 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.83514 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 2.80354 |
| KLHL9 | kelch-like family member 9 | 2.78754 |
| ATP11B | ATPase, class VI, type 11B | 2.74821 |
| PLS1 | plastin 1 | 2.74739 |
| CEP57 | centrosomal protein 57kDa | 2.58344 |
| GATA2 | GATA binding protein 2 | 2.58065 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.56902 |
| CYCS | cytochrome c, somatic | 2.47386 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.42685 |
| CSK | c-src tyrosine kinase | 2.29491 |
| NOTCH1 | notch 1 | 2.20727 |
| TBX19 | T-box 19 | 2.07643 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.0711 |
| HCAR3 | hydroxycarboxylic acid receptor 3 | 2.03489 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.92777 |
| LDHD | lactate dehydrogenase D | -6.83125 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -6.03334 |
| MAPK13 | mitogen-activated protein kinase 13 | -5.81539 |
| GNAS | GNAS complex locus | -5.16094 |
| MRPS2 | mitochondrial ribosomal protein S2 | -5.08481 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -5.07921 |
| TLR4 | toll-like receptor 4 | -4.52638 |
| PCNA | proliferating cell nuclear antigen | -4.22747 |
| ZNF586 | zinc finger protein 586 | -4.16456 |
| FASTKD5 | FAST kinase domains 5 | -3.86734 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.64056 |
| TLCD3A | TLC domain containing 3A | -3.62188 |
| WASHC4 | WASH complex subunit 4 | -3.47131 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.38675 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.07157 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.78972 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.75941 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.69709 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.6002 |
| SNX11 | sorting nexin 11 | -2.44236 |
| NGRN | neugrin, neurite outgrowth associated | -2.29432 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -2.26017 |
| MEF2B | myocyte enhancer factor 2B | -2.16842 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 | -2.14927 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.14745 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) | -2.13021 |
| RBM6 | RNA binding motif protein 6 | -2.06455 |
| LIPG | lipase, endothelial | -2.04355 |
| PRPF4 | pre-mRNA processing factor 4 | -2.01322 |
