| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | triclosan 2.5 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN010_HEPG2_24H:H11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAMLD1 | mastermind-like domain containing 1 | 6.77771 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 6.46908 |
| NOTCH1 | notch 1 | 6.0674 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.63527 |
| MYLK | myosin light chain kinase | 5.60314 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.22664 |
| KLHL21 | kelch-like family member 21 | 3.97821 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 3.82551 |
| MEST | mesoderm specific transcript | 3.81821 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 3.79182 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.68014 |
| ATP11B | ATPase, class VI, type 11B | 3.34595 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.31049 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.22493 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 3.19645 |
| SOCS2 | suppressor of cytokine signaling 2 | 3.09589 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.09092 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.91302 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.67487 |
| CORO1A | coronin, actin binding protein, 1A | 2.60016 |
| MSRA | methionine sulfoxide reductase A | 2.59332 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.49829 |
| PIH1D1 | PIH1 domain containing 1 | 2.39557 |
| HSPA12A | heat shock 70kDa protein 12A | 2.36334 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 2.29728 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 2.26778 |
| WDR7 | WD repeat domain 7 | 2.24436 |
| ECT2 | epithelial cell transforming 2 | 2.14236 |
| PNKP | polynucleotide kinase 3'-phosphatase | 2.13323 |
| ERI2 | ERI1 exoribonuclease family member 2 | 2.11617 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 2.11036 |
| GLOD4 | glyoxalase domain containing 4 | 2.10027 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 2.09777 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 2.0368 |
| VGLL4 | vestigial-like family member 4 | 2.02304 |
| FMNL3 | formin-like 3 | 2.00574 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -7.52819 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -6.60673 |
| TLR4 | toll-like receptor 4 | -6.58422 |
| SLC35F2 | solute carrier family 35, member F2 | -4.83532 |
| GNAS | GNAS complex locus | -4.74948 |
| NRIP1 | nuclear receptor interacting protein 1 | -4.38127 |
| VDAC1 | voltage-dependent anion channel 1 | -4.20808 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -4.20087 |
| LDHD | lactate dehydrogenase D | -3.86374 |
| ZNF586 | zinc finger protein 586 | -3.77195 |
| DNM1L | dynamin 1-like | -3.76637 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -3.35633 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.22165 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.17365 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.02873 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.02207 |
| FASTKD5 | FAST kinase domains 5 | -2.85741 |
| CDC25B | cell division cycle 25B | -2.82259 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.67652 |
| CAB39 | calcium binding protein 39 | -2.6187 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.58192 |
| TCTN1 | tectonic family member 1 | -2.5241 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.40478 |
| PCDHB12 | protocadherin beta 12 | -2.30273 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -2.29969 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.28223 |
| SNRNP35 | small nuclear ribonucleoprotein 35kDa (U11/U12) | -2.2536 |
| DUSP6 | dual specificity phosphatase 6 | -2.24277 |
| SESN1 | sestrin 1 | -2.12607 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.09418 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.05208 |
| LOC100533997 | MAGEA10-MAGEA5 readthrough | -2.04321 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.00449 |
| FHL2 | four and a half LIM domains 2 | -2.00244 |
