| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | chlorendic acid 39.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN010_HEPG2_24H:H13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 9.02216 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.31973 |
| GPER1 | G protein-coupled estrogen receptor 1 | 5.16458 |
| MAP7 | microtubule-associated protein 7 | 5.0836 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 5.04892 |
| PLS1 | plastin 1 | 5.02742 |
| CCNF | cyclin F | 4.44676 |
| CYCS | cytochrome c, somatic | 4.35754 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.10926 |
| PRR15L | proline rich 15-like | 3.91746 |
| SOCS2 | suppressor of cytokine signaling 2 | 3.8052 |
| JADE2 | jade family PHD finger 2 | 3.61167 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 3.23643 |
| NOSIP | nitric oxide synthase interacting protein | 3.17273 |
| KLHL9 | kelch-like family member 9 | 3.10998 |
| TXNL4B | thioredoxin-like 4B | 2.82967 |
| SFTPB | surfactant protein B | 2.78518 |
| RAB21 | RAB21, member RAS oncogene family | 2.64306 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.61028 |
| PLSCR3 | phospholipid scramblase 3 | 2.56922 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.55173 |
| NDUFS5 | NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) | 2.48426 |
| TSPAN6 | tetraspanin 6 | 2.4813 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.41429 |
| FZD1 | frizzled class receptor 1 | 2.41315 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 | 2.36468 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 2.32784 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.27791 |
| TET3 | tet methylcytosine dioxygenase 3 | 2.19701 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 2.17933 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 2.16038 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | 2.14354 |
| NUCB2 | nucleobindin 2 | 2.141 |
| SLC17A4 | solute carrier family 17, member 4 | 2.09159 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 2.07536 |
| ZFAND1 | zinc finger, AN1-type domain 1 | 2.03317 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 2.00231 |
| Symbol | Name | Standardized Value |
|---|---|---|
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -5.54905 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.53301 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.2893 |
| TSPAN4 | tetraspanin 4 | -5.22252 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -5.0123 |
| CCDC86 | coiled-coil domain containing 86 | -4.99804 |
| CCNB2 | cyclin B2 | -4.90088 |
| RNF167 | ring finger protein 167 | -4.7592 |
| PLK1 | polo-like kinase 1 | -4.41096 |
| LDHD | lactate dehydrogenase D | -4.36665 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.64578 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.64306 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.59236 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.56603 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.32865 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.29338 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -2.76135 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.75885 |
| TLR4 | toll-like receptor 4 | -2.64766 |
| CD58 | CD58 molecule | -2.6014 |
| ICAM3 | intercellular adhesion molecule 3 | -2.56161 |
| TWF2 | twinfilin actin binding protein 2 | -2.54401 |
| CAB39 | calcium binding protein 39 | -2.48597 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.32039 |
| CCND3 | cyclin D3 | -2.28798 |
| BCKDK | branched chain ketoacid dehydrogenase kinase | -2.24252 |
| MTA1 | metastasis associated 1 | -2.19487 |
| PEG10 | paternally expressed 10 | -2.18654 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | -2.16954 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.13616 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) | -2.13099 |
| ADI1 | acireductone dioxygenase 1 | -2.04689 |
| PLAC1 | placenta-specific 1 | -2.02093 |
