CRCGN010_HEPG2_24H:H14 Gene Set
Genes
55 genes differentially expressed following the CRCGN010_HEPG2_24H:H14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GATA3
|
GATA binding protein 3
|
6.15757
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.04776
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.93663
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.85123
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.72107
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
3.67294
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.66341
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
3.48872
|
|
LCN2
|
lipocalin 2
|
3.44764
|
|
HOXA10
|
homeobox A10
|
3.22899
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
3.16426
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.08895
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
2.69477
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.58505
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.5068
|
|
ABHD4
|
abhydrolase domain containing 4
|
2.39305
|
|
MEST
|
mesoderm specific transcript
|
2.34828
|
|
STIMATE
|
STIM activating enhancer
|
2.33715
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.28625
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.27426
|
|
CCNF
|
cyclin F
|
2.26393
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.18999
|
|
ZNF589
|
zinc finger protein 589
|
2.1423
|
|
SHB
|
Src homology 2 domain containing adaptor protein B
|
2.13221
|
|
STXBP2
|
syntaxin binding protein 2
|
2.13062
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.09929
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-7.29423
|
|
ISOC1
|
isochorismatase domain containing 1
|
-6.00932
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.51858
|
|
NUP93
|
nucleoporin 93kDa
|
-3.91054
|
|
ZNF586
|
zinc finger protein 586
|
-3.89391
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.80263
|
|
GNAS
|
GNAS complex locus
|
-3.55657
|
|
LDHD
|
lactate dehydrogenase D
|
-3.521
|
|
DSG2
|
desmoglein 2
|
-3.32636
|
|
MTFR1
|
mitochondrial fission regulator 1
|
-3.15773
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.05065
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.01953
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.77447
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.77176
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.68316
|
|
DNM1L
|
dynamin 1-like
|
-2.66837
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.56313
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.48634
|
|
ASAH1
|
N-acylsphingosine amidohydrolase (acid ceramidase) 1
|
-2.4818
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.38604
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.22164
|
|
CNNM1
|
cyclin and CBS domain divalent metal cation transport mediator 1
|
-2.19904
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.17303
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.14013
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.13741
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.12306
|
|
CDC25B
|
cell division cycle 25B
|
-2.06889
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.05062
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-2.00192
|
