CRCGN010_HEPG2_24H:H17 Gene Set
Genes
58 genes differentially expressed following the CRCGN010_HEPG2_24H:H17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
5.99456
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
5.10912
|
|
LCN2
|
lipocalin 2
|
5.07433
|
|
CSK
|
c-src tyrosine kinase
|
4.89405
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.73422
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.6629
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.50182
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.35283
|
|
MAP7
|
microtubule-associated protein 7
|
4.2748
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
3.88863
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.73226
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
3.72844
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.65725
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
3.60479
|
|
CEP57
|
centrosomal protein 57kDa
|
3.50931
|
|
EVL
|
Enah/Vasp-like
|
3.34771
|
|
MICALL1
|
MICAL-like 1
|
3.28318
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.12477
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.9443
|
|
KLHL9
|
kelch-like family member 9
|
2.72034
|
|
CHEK2
|
checkpoint kinase 2
|
2.6807
|
|
GPATCH8
|
G patch domain containing 8
|
2.66219
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.60097
|
|
NDUFAF3
|
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
|
2.40941
|
|
PAAF1
|
proteasomal ATPase-associated factor 1
|
2.23815
|
|
ABHD11
|
abhydrolase domain containing 11
|
2.1984
|
|
NISCH
|
nischarin
|
2.16669
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.15576
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
2.082
|
|
RSAD2
|
radical S-adenosyl methionine domain containing 2
|
2.07183
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.07015
|
|
ADAM10
|
ADAM metallopeptidase domain 10
|
2.05037
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLCD3A
|
TLC domain containing 3A
|
-7.05963
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-5.56035
|
|
SLC35A1
|
solute carrier family 35 (CMP-sialic acid transporter), member A1
|
-5.49656
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.28384
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-5.19724
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-4.61652
|
|
PLK1
|
polo-like kinase 1
|
-4.30559
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-3.78554
|
|
RNF167
|
ring finger protein 167
|
-3.40029
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.85913
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.7517
|
|
HMG20B
|
high mobility group 20B
|
-2.70029
|
|
ZNF586
|
zinc finger protein 586
|
-2.58064
|
|
GET3
|
guided entry of tail-anchored proteins factor 3, ATPase
|
-2.51542
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-2.4753
|
|
HSPA4
|
heat shock 70kDa protein 4
|
-2.42177
|
|
SESN1
|
sestrin 1
|
-2.31466
|
|
MAPKAP1
|
mitogen-activated protein kinase associated protein 1
|
-2.1753
|
|
CCT7
|
chaperonin containing TCP1, subunit 7 (eta)
|
-2.13481
|
|
EPHX3
|
epoxide hydrolase 3
|
-2.09944
|
|
CRTAP
|
cartilage associated protein
|
-2.09725
|
|
PDZD2
|
PDZ domain containing 2
|
-2.07998
|
|
DSE
|
dermatan sulfate epimerase
|
-2.0451
|
|
POLE
|
polymerase (DNA directed), epsilon, catalytic subunit
|
-2.03306
|
|
BCAS3
|
breast carcinoma amplified sequence 3
|
-2.01734
|
|
RAB9A
|
RAB9A, member RAS oncogene family
|
-2.01432
|
